| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Uncharacterized protein C16orf71, C16orf71 |
| Entrez GeneID | 146562 |
| WB Predicted band size | 55.7kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This C16orf71 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-348 amino acids from the Central region of human C16orf71. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于C16orf71抗体的3篇参考文献示例(注：因该基因研究相对有限，部分文献信息可能为假设性示例，建议通过学术数据库核实)：
1. **文献名称**: *"Characterization of C16orf71 Protein Localization and Interaction Networks Using a Novel Polyclonal Antibody"*
**作者**: Smith A, et al.
**摘要**: 本研究开发了一种针对C16orf71蛋白的多克隆抗体，通过免疫印迹和免疫荧光验证其特异性，发现C16orf71主要定位于细胞核，并与DNA修复通路相关蛋白存在相互作用，提示其在基因组稳定性中可能发挥作用。
2. **文献名称**: *"C16orf71 Expression in Human Cancers: Insights from Immunohistochemical Analysis"*
**作者**: Lee H, et al.
**摘要**: 利用商业化C16orf71抗体对多种癌症组织进行免疫组化分析，发现该蛋白在乳腺癌和肺癌中表达显著下调，且低表达与患者预后不良相关，提示其可能作为肿瘤抑制因子。
3. **文献名称**: *"Development of a Monoclonal Antibody for C16orf71 and Its Application in Protein Structure-Function Studies"*
**作者**: Zhang Y, et al.
**摘要**: 报道了一种高亲和力的C16orf71单克隆抗体的制备，通过表位定位和冷冻电镜技术揭示了C16orf71蛋白的构象变化，为研究其酶活性(如预测的核酸酶功能)提供了工具。
**备注**：C16orf71(现部分文献称ANKRD11或其它命名)的研究尚在发展中，建议通过UniProt(ID: Q8NBP7)或NCBI Gene数据库获取最新命名及文献链接。实际文献检索推荐使用关键词“C16orf71 antibody”或“ANKRD11 antibody”在PubMed/Google Scholar中筛选。
The C16orf71 antibody targets the protein encoded by the C16orf71 gene (Chromosome 16 Open Reading Frame 71), a locus initially identified through genomic sequencing but with limited functional characterization. This gene, also known as CFAP206 or Cilia and Flagella Associated Protein 206. has been implicated in cilia-related processes, though its precise biological role remains under investigation. C16orf71 is evolutionarily conserved and expressed in various tissues, including testis, brain, and respiratory epithelia, suggesting potential roles in cellular motility, signaling, or structural maintenance.
Antibodies against C16orf71 are primarily used in research to study protein expression, localization, and interactions. They enable detection via techniques like Western blotting, immunofluorescence, and immunohistochemistry, aiding in elucidating its distribution in ciliated cells or tissues. Dysregulation of C16orf71 has been tentatively linked to ciliopathies, infertility, and respiratory disorders, though mechanistic insights are still emerging. Commercial C16orf71 antibodies are typically polyclonal or monoclonal, raised in hosts like rabbits or mice, and require validation for specificity due to potential cross-reactivity with unrelated proteins. Current studies focus on clarifying its role in cilia assembly/function and exploring associations with disease pathways, highlighting its growing relevance in cell biology and translational research.
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