| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Olfactory receptor 6S1, Olfactory receptor OR14-37, OR6S1 |
| Entrez GeneID | 341799 |
| WB Predicted band size | 36.1kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This OR6S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-310 amino acids from the C-terminal region of human OR6S1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于OR6S1(C-term)抗体的**模拟参考文献示例**(非真实文献，仅供格式参考)：
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1. **文献名称**: "Characterization of OR6S1 C-terminal antibody in olfactory receptor signaling"
**作者**: Smith A, et al.
**摘要**: 本研究验证了OR6S1(C-term)抗体的特异性，通过Western blot和免疫荧光证实其在嗅觉上皮组织中的表达，并发现OR6S1可能参与非嗅觉组织的化学感应信号通路。
2. **文献名称**: "OR6S1 expression in gastrointestinal tumors and its clinical relevance"
**作者**: Zhang L, et al.
**摘要**: 利用OR6S1(C-term)抗体进行免疫组化分析，发现OR6S1在结直肠癌中异常高表达，且与患者预后相关，提示其作为潜在生物标志物的可能性。
3. **文献名称**: "A novel role of OR6S1 in metabolic regulation: Insights from C-terminal antibody-based studies"
**作者**: Johnson R, et al.
**摘要**: 通过OR6S1(C-term)抗体筛选小鼠肝脏组织，发现该受体与脂质代谢相关蛋白存在相互作用，为代谢疾病研究提供了新方向。
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**注意**：以上文献为虚构示例，实际研究中OR6S1相关抗体文献可能较少。建议通过**PubMed**或**Google Scholar**搜索关键词(如"OR6S1 antibody C-terminal")获取真实文献，或参考抗体供应商(如Abcam、Sigma-Aldrich)提供的技术文档。
The OR6S1 (C-term) antibody is designed to target the C-terminal region of the olfactory receptor 6S1 (OR6S1), a member of the olfactory receptor (OR) family, which constitutes the largest group of G protein-coupled receptors (GPCRs). Olfactory receptors are primarily expressed in olfactory sensory neurons, where they detect odorant molecules and initiate signal transduction. However, emerging studies suggest ectopic expression of ORs in non-olfactory tissues, implicating roles in physiological processes such as cell migration, proliferation, and cancer progression. OR6S1. specifically, remains understudied, with limited data on its precise functional roles or ligand specificity.
The C-terminal domain of OR6S1 is critical for intracellular signaling, as it interacts with downstream effectors like G proteins and regulatory proteins involved in receptor trafficking and desensitization. Antibodies targeting this region (e.g., OR6S1 C-term) are valuable tools for investigating the receptor’s expression patterns, subcellular localization, and post-translational modifications. Such antibodies are typically validated via Western blotting, immunohistochemistry, or immunofluorescence to confirm specificity, often using cell lines overexpressing OR6S1 or tissues with known expression.
Research applications include exploring OR6S1’s potential roles in non-olfactory contexts, such as cancer or metabolic regulation. Challenges include the high sequence homology among OR family members, necessitating rigorous validation to ensure minimal cross-reactivity. Overall, OR6S1 (C-term) antibodies provide a molecular foothold to decode the enigmatic functions of this receptor in health and disease.
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