| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | GASR, CCK-B, CCK2R |
| WB Predicted band size | 49 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide of human CCKBR |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于ZNF337(C-term)抗体的参考文献示例(注：以下内容为模拟生成，实际文献可能需要通过学术数据库检索确认)：
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1. **"Characterization of ZNF337 in transcriptional regulation and cancer progression"**
*Authors: Smith J, Lee K, et al.*
**摘要**：本研究利用ZNF337(C-term)抗体通过Western blot和免疫组化分析了ZNF337在多种癌细胞系中的表达，发现其高表达与肿瘤侵袭性相关，并证实抗体特异性可用于染色质免疫沉淀(ChIP)实验以研究其靶基因。
2. **"A novel zinc finger protein ZNF337 interacts with β-catenin in Wnt signaling"**
*Authors: Wang Y, Zhang R, et al.*
**摘要**：文章通过免疫共沉淀(Co-IP)和免疫荧光技术，使用ZNF337(C-term)抗体验证了ZNF337与β-catenin的相互作用，揭示了其在Wnt信号通路中的调控作用，抗体特异性经siRNA敲低实验验证。
3. **"Development and validation of polyclonal antibodies against ZNF337 for functional studies"**
*Authors: Gonzalez M, Patel S, et al.*
**摘要**：本研究详细描述了针对ZNF337 C末端多肽的抗体制备过程，验证了抗体在ELISA、免疫组化和流式细胞术中的应用，并证明其适用于检测内源性ZNF337蛋白表达。
4. **"ZNF337 regulates oxidative stress response via NRF2 pathway modulation"**
*Authors: Tanaka H, Kimura T, et al.*
**摘要**：通过ZNF337(C-term)抗体的Western blot和免疫荧光分析，研究发现ZNF337通过调控NRF2通路影响细胞氧化应激反应，抗体特异性通过CRISPR敲除细胞系得到验证。
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**注意**：以上文献为示例，实际引用时请通过PubMed、Google Scholar等平台检索真实文献(关键词：ZNF337 antibody C-terminal)，并确认抗体应用场景(如WB/IHC/IF等)及实验验证细节。
The ZNF337 (C-term) antibody is designed to target the C-terminal region of the zinc finger protein 337 (ZNF337), a member of the zinc finger protein family characterized by conserved cysteine and histidine residues that facilitate DNA binding and transcriptional regulation. ZNF337 is implicated in various cellular processes, including gene expression modulation, cell differentiation, and potential roles in oncogenesis. The C-terminal domain often contains functional motifs critical for protein-protein interactions or DNA binding, making antibodies against this region valuable for studying ZNF337's molecular mechanisms.
This antibody is commonly used in applications such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to detect endogenous ZNF337 expression in human or murine samples. Its specificity for the C-terminus helps distinguish ZNF337 from other zinc finger proteins, aiding in research on its tissue distribution, subcellular localization, and expression patterns under different physiological or pathological conditions.
Studies suggest ZNF337 may be involved in tumor progression, with altered expression observed in certain cancers, though its precise biological and pathological roles remain under investigation. Researchers utilize the ZNF337 (C-term) antibody to explore its interactions with downstream targets, regulatory pathways, and potential as a biomarker. Validation typically includes knockout/knockdown controls or peptide blocking assays to confirm specificity. As a tool, it supports both basic research and translational studies aiming to elucidate ZNF337's contributions to development, disease, and cellular homeostasis.
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