| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Perilipin-3, Cargo selection protein TIP47, Mannose-6-phosphate receptor-binding protein 1, Plin3, M6prbp1, Tip47 |
| Entrez GeneID | 66905 |
| WB Predicted band size | 47.3kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This Mouse Plin3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-322 amino acids from the C-terminal region of mouse Plin3. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是与小鼠Plin3(C端)抗体相关的3篇文献示例(注：文献为虚构示例，仅供参考)：
1. **文献名称**: *"Plin3 regulates lipid droplet dynamics in adipose tissue macrophages"*
**作者**: Lee et al. (2020)
**摘要**: 本研究利用针对Plin3 C端的特异性抗体，通过免疫荧光和Western blot技术，揭示了Plin3在巨噬细胞脂滴形成中的关键作用，并发现其缺失加剧肥胖相关炎症。
2. **文献名称**: *"C-terminal epitope-specific antibody reveals Plin3 localization in hepatic steatosis"*
**作者**: Garcia-Ruiz et al. (2018)
**摘要**: 通过小鼠模型，使用抗Plin3 C端抗体进行组织免疫组化分析，发现Plin3在脂肪肝中的表达显著上调，且与脂滴大小和肝脏脂质沉积程度呈正相关。
3. **文献名称**: *"Role of Plin3 in adipocyte lipolysis: Insights from antibody-based perturbation studies"*
**作者**: Müller et al. (2016)
**摘要**: 利用Plin3(C-term)抗体阻断其功能，证明Plin3通过调控脂滴表面蛋白相互作用抑制脂肪分解，为代谢疾病治疗提供新靶点。
**注**：以上文献为模拟示例，实际研究中需通过PubMed或Google Scholar以关键词“Plin3 C-terminal antibody”、“mouse Plin3”等检索真实文献。
The Mouse Plin3 (C-term) antibody is a monoclonal antibody specifically designed to detect the C-terminal region of Perilipin 3 (PLIN3), a lipid droplet-associated protein involved in lipid metabolism and storage. PLIN3. also known as TIP47. plays a critical role in stabilizing lipid droplets and regulating intracellular lipid trafficking, particularly in non-adipocyte cells such as hepatocytes, macrophages, and steroidogenic cells. It is implicated in metabolic disorders, including obesity, atherosclerosis, and non-alcoholic fatty liver disease (NAFLD).
This antibody is commonly used in research applications such as Western blotting, immunofluorescence, and immunohistochemistry to study PLIN3 expression, localization, and function under various physiological or pathological conditions. Its specificity for the C-terminal domain ensures recognition of full-length PLIN3. avoiding cross-reactivity with other Perilipin family members (e.g., PLIN1. PLIN2). Validation typically includes testing in PLIN3-knockout cell lines or tissues to confirm absence of non-specific binding.
Studies utilizing this antibody have contributed to understanding lipid droplet dynamics, cellular stress responses, and metabolic dysregulation, making it a valuable tool for investigating molecular mechanisms underlying lipid-related diseases. Proper experimental controls, such as peptide competition assays, are recommended to ensure result accuracy.
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