关键信息
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基因名
CDCA8
- 应用
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别名
CDCA8；PESCRG3；Borealin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q53HL2
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表达区间
1-280aa
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氨基酸序列
MAPRKGSSRV AKTNSLRRRK LASFLKDFDR EVEIRIKQIE SDRQNLLKEV DNLYNIEILR LPKALREMNW LDYFALGGNK QALEEAATAD LDITEINKLT AEAIQTPLKS AKTRKVIQVD EMIVEEEEEE ENERKNLQTA RVKRCPPSKK RTQSIQGKGK GKRSSRANTV TPAVGRLEVS MVKPTPGLTP RFDSRVFKTP GLRTPAAGER IYNISGNGSP LADSKEIFLT VPVGGGESLR LLASDLQRHS IAQLDPEALG NIKKLSNRLA QICSSIRTHK
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CDCA8, also known as Cell Division Cycle Associated Protein 8, plays a crucial role in the regulation of mitosis, particularly during the processes of chromosome alignment and segregation. As a part of the chromosomal passenger complex, CDCA8 is essential for accurate chromosome segregation and is closely linked to the function of the protein Aurora B kinase. Dysregulation of CDCA8 is associated with various types of cancer, making it a potential target for therapeutic intervention. Recent studies have focused on the characterization and expression of recombinant CDCA8 proteins to elucidate its functional mechanisms and interaction partners. This research aims to better understand its role in cell cycle regulation, as well as its contribution to oncogenic processes. By investigating the structural and functional attributes of CDCA8 through recombinant technology, researchers hope to identify novel strategies for cancer treatment and diagnosis, thereby enhancing our understanding of tumor biology and improving patient outcomes.
