| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Inhibin alpha chain, Inha |
| Entrez GeneID | 16322 |
| WB Predicted band size | 39.6kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Mouse |
| Immunogen | This Mouse Inha antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-64 amino acids from the N-terminal region of mouse Inha. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
+ +
以下是关于 **Mouse Inha (N-term) 抗体** 的模拟参考文献示例(仅供格式参考，非真实文献)：
---
1. **文献名称**: *Localization of Inhibin Alpha Subunit in Mouse Ovarian Follicles Using a Novel N-terminal Specific Antibody*
**作者**: Smith A, et al.
**摘要**: 本研究利用针对小鼠抑制素α亚基N端区域的抗体，通过免疫组织化学技术揭示了其在卵巢颗粒细胞中的特异性表达，为研究卵泡发育提供了分子标记。
2. **文献名称**: *Characterization of Inhibin Alpha Knockout Mice: Role in Reproductive Dysfunction*
**作者**: Brown L, et al.
**摘要**: 通过Western blot和免疫荧光技术，使用N端特异性抗体检测了基因敲除小鼠模型中抑制素α的表达缺失，证实其在生殖激素调控中的关键作用。
3. **文献名称**: *Differential Expression of Inhibin Alpha in Mouse Testicular Tumors*
**作者**: Chen W, et al.
**摘要**: 利用抗小鼠Inha (N-term)抗体进行免疫印迹分析，发现抑制素α在睾丸支持细胞瘤中高表达，提示其作为肿瘤标志物的潜在价值。
4. **文献名称**: *Development and Validation of a Mouse-Specific Inhibin Alpha Antibody for Embryonic Studies*
**作者**: Kim Y, et al.
**摘要**: 报道了一种高特异性小鼠Inha N端抗体的制备与验证，该抗体成功用于胚胎发育过程中抑制素α的动态表达分析。
---
### 注意事项：
- 以上为模拟示例，真实文献需通过 **PubMed**、**Google Scholar** 或抗体供应商官网(如Abcam、Thermo Fisher等)检索，关键词：`Mouse Inhibin alpha antibody N-term`。
- 部分抗体文献可能发表于技术期刊或厂商手册，建议结合具体实验需求筛选。
The Mouse Inha (N-term) antibody is designed to specifically target the N-terminal region of the inhibin alpha subunit (Inha) in mice. Inhibins are dimeric glycoproteins belonging to the TGF-β (transforming growth factor-beta) superfamily, composed of an alpha subunit (Inha) and one of two beta subunits (βA or βB), forming inhibin A (α-βA) or inhibin B (α-βB). These hormones play critical roles in regulating reproductive physiology, particularly by suppressing follicle-stimulating hormone (FSH) secretion from the pituitary gland. The alpha subunit is essential for the bioactivity of inhibins and is expressed predominantly in gonadal tissues, though it is also detected in adrenal glands, placenta, and certain tumors.
The antibody’s specificity for the N-terminal region ensures recognition of intact inhibins and pro-form precursors, making it useful in studies involving gonadal development, fertility, and hormone-dependent cancers. Researchers employ this antibody in techniques like Western blotting, immunohistochemistry, and ELISA to analyze Inha expression patterns, protein localization, and its regulatory roles in reproductive and endocrine pathways. Its application in mouse models helps elucidate mechanisms underlying disorders like premature ovarian failure, polycystic ovary syndrome (PCOS), and granulosa cell tumors. Validation typically includes testing on recombinant Inha or tissue lysates from Inha-expressing organs to confirm reactivity and absence of cross-reactivity with related TGF-β family members.
×
