Rabbit Polyclonal MouseRpl9 Antibody

The Mouse Rpl9 antibody is a tool designed to detect ribosomal protein L9 (Rpl9), a component of the 60S ribosomal subunit in mice. Rpl9 plays a critical role in protein synthesis by contributing to ribosome structure and facilitating rRNA binding during translation. This antibody is commonly used in research to study ribosome biogenesis, cellular stress responses, and translational regulation in mouse models. It is often generated in hosts such as rabbits or mice, with specificity validated through techniques like Western blotting, immunohistochemistry (IHC), or immunofluorescence (IF). The antibody typically recognizes the mouse Rpl9 protein (approximately 21-23 kDa) and may exhibit cross-reactivity with orthologs in other species, depending on epitope conservation. Researchers employ it in contexts like cancer studies, neurodegenerative disease models, or metabolic disorders where ribosomal dysfunction is implicated. Quality control often includes testing in Rpl9-knockout systems to confirm specificity. Its applications extend to exploring how Rpl9 expression varies under physiological or pathological conditions, offering insights into cellular proliferation, apoptosis, and stress adaptation mechanisms.