Rabbit Polyclonal LRRC39(N-term) Antibody

The LRRC39 (N-term) antibody is a specific immunological tool designed to target the N-terminal region of the leucine-rich repeat-containing protein 39 (LRRC39). LRRC39 belongs to the leucine-rich repeat (LRR) family, characterized by tandem repeats of 20–30 amino acids rich in leucine residues, which are often involved in protein-protein interactions, signal transduction, or structural organization. The N-terminal region of LRRC39 may contain critical functional domains or binding motifs that contribute to its biological role, though its precise molecular mechanisms remain under investigation. This antibody is commonly used in techniques like Western blotting, immunoprecipitation, or immunofluorescence to study LRRC39's expression, localization, and interactions in various tissues or cell types. Research suggests LRRC39 may play roles in cellular processes such as ciliogenesis, immune regulation, or cell cycle control, with potential links to ciliopathies, inflammatory diseases, or cancer. The antibody's specificity for the N-terminal epitope helps distinguish LRRC39 from other LRR family members, enabling accurate detection in complex biological samples. Validation typically includes testing in knockout models or siRNA-treated cells to confirm target specificity. Its development supports ongoing efforts to elucidate LRRC39's physiological and pathological significance.