WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Membrane protein MLC1, MLC1, KIAA0027, WKL1 |
Entrez GeneID | 23209 |
WB Predicted band size | 41.1kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This MLC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the C-terminal region of human MLC1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是3-4条关于MLC1抗体的假设参考文献示例,供参考:
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1. **文献名称**:*"MLC1 Antibody Characterization in Megalencephalic Leukoencephalopathy Diagnosis"*
**作者**:Van der Knaap, M.S. et al.
**摘要**:本研究开发了一种特异性抗MLC1抗体,用于检测患者脑组织或血细胞中MLC1蛋白的异常表达,证实其在遗传性脑白质病(MLC)中的诊断价值,并揭示了蛋白定位缺陷与基因突变的关联。
2. **文献名称**:*"Role of MLC1 in Astrocyte Volume Regulation: Insights from Antibody-Based Imaging"*
**作者**:Ridder, M.C. et al.
**摘要**:通过免疫荧光和Western blot技术,利用MLC1抗体揭示其在星形胶质细胞中的表达模式,证明MLC1参与细胞容积调节,突变导致渗透压敏感性异常,可能与脑水肿病理机制相关。
3. **文献名称**:*"A Novel Monoclonal Antibody for MLC1 Quantification in Cerebrospinal Fluid"*
**作者**:Sánchez-Olea, R. et al.
**摘要**:报道一种新型单克隆抗体的制备,可高灵敏度检测脑脊液中MLC1水平,为MLC疾病的非侵入性诊断及疗效监测提供潜在生物标志物。
4. **文献名称**:*"MLC1 Interaction with Tight Junction Proteins Revealed by Co-Immunoprecipitation"*
**作者**:Dubey, M. et al.
**摘要**:利用MLC1抗体进行免疫共沉淀实验,发现其与紧密连接蛋白(如Claudin-1)的相互作用,提示MLC1在血脑屏障功能中的潜在作用及突变导致神经退化的分子机制。
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**注**:以上文献为示例性质,若需真实文献,建议通过PubMed或Google Scholar检索关键词“MLC1 antibody”或“MLC1 protein function”获取最新研究。
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