| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Armadillo repeat-containing protein 10, Splicing variant involved in hepatocarcinogenesis protein, ARMC10, SVH |
| Entrez GeneID | 83787 |
| WB Predicted band size | 37.5kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This ARMC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-86 amino acids from the N-terminal region of human ARMC10. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于ARMC10 (N-term)抗体的参考文献示例(注：以下内容为虚构，仅作格式示范)：
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1. **文献名称**：*ARMC10 modulates mitochondrial morphology and promotes tumor metastasis*
**作者**：Chen L, et al.
**摘要**：本研究利用ARMC10 (N-term)抗体进行免疫印迹和免疫荧光实验，发现ARMC10通过调控线粒体分裂蛋白Drp1的活性，影响线粒体形态，进而促进乳腺癌细胞的侵袭转移。
2. **文献名称**：*ARMC10 interacts with β-catenin to regulate Wnt signaling in colorectal cancer*
**作者**：Wang X, et al.
**摘要**：通过ARMC10 (N-term)抗体的免疫共沉淀实验，揭示了ARMC10与β-catenin的相互作用，并证明其通过稳定β-catenin增强Wnt信号通路，促进结直肠癌细胞增殖。
3. **文献名称**：*ARMC10 expression in glioblastoma: A prognostic biomarker study*
**作者**：Garcia R, et al.
**摘要**：采用ARMC10 (N-term)抗体对胶质母细胞瘤组织进行免疫组化分析，发现高表达ARMC10与患者总生存期缩短显著相关，提示其作为潜在预后标志物的价值。
4. **文献名称**：*ARMC10 mediates cellular stress response via autophagy regulation*
**作者**：Kim S, et al.
**摘要**：利用ARMC10 (N-term)抗体检测蛋白表达，发现ARMC10通过调控自噬相关蛋白LC3-II的加工，参与细胞在营养剥夺条件下的应激存活机制。
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**注**：以上文献为示例，实际引用需查询真实数据库(如PubMed)。建议通过关键词“ARMC10 antibody N-terminal”或抗体货号(如Abcam#12345)检索具体文献。
The ARMC10 (N-term) antibody is a tool designed to target the N-terminal region of the ARMC10 protein, a member of the armadillo repeat (ARM)-containing protein family. ARMC10 is a relatively understudied protein implicated in diverse cellular processes, including mitochondrial dynamics, apoptosis, and cell proliferation. Its N-terminal domain contains conserved ARM repeats, which are structural motifs involved in protein-protein interactions, suggesting a role in scaffolding or signaling complexes.
Studies suggest ARMC10 localizes to mitochondria and may regulate mitochondrial morphology by interacting with fusion/fission machinery. Dysregulation of ARMC10 has been linked to cancer progression, with altered expression observed in certain malignancies, though its precise mechanisms remain unclear. The ARMC10 (N-term) antibody is commonly used in techniques like Western blotting, immunoprecipitation, and immunofluorescence to detect endogenous protein expression, assess subcellular localization, or study interactions in model systems.
This antibody is particularly valuable in exploring ARMC10’s functional roles in mitochondrial biology and disease contexts. Researchers utilize it to investigate correlations between ARMC10 expression patterns and clinical outcomes in cancer, neurodegenerative disorders, or metabolic diseases. However, due to limited characterization of ARMC10. validation of antibody specificity (e.g., via knockout controls) is critical. Ongoing research aims to clarify ARMC10’s molecular functions and therapeutic potential, positioning this antibody as a key reagent in unraveling its biological significance.
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