| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | 40S ribosomal protein S23, RPS23 |
| Entrez GeneID | 6228 |
| WB Predicted band size | 15.8kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This RPS23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human RPS23. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于RPS23 (N-term)抗体的3篇参考文献及其摘要内容(注：以下为模拟文献，实际文献需通过学术数据库查询确认)：
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1. **文献名称**：*RPS23 N-terminal antibody application in detecting ribosome biogenesis defects in human cells*
**作者**：Chen, L., et al.
**摘要**：本研究利用针对RPS23蛋白N端的特异性抗体，通过免疫印迹和免疫荧光技术，揭示了RPS23在核糖体组装过程中的关键作用。实验表明，RPS23缺失会导致核仁结构异常，并显著抑制癌细胞增殖，为靶向核糖体蛋白的癌症治疗提供了潜在依据。
2. **文献名称**：*Development and validation of a polyclonal antibody targeting the N-terminal region of RPS23 for neurodegenerative disease research*
**作者**：Martinez, R., et al.
**摘要**：该文献报道了一种针对RPS23蛋白N端表位的多克隆抗体的开发与验证。通过ELISA和免疫组化实验证实了抗体的高特异性，并应用于阿尔茨海默病模型小鼠脑组织检测，发现RPS23表达水平与神经元退行性病变呈负相关。
3. **文献名称**：*RPS23 interacts with viral RNA and modulates host antiviral response: Evidence from N-terminal-specific antibody blocking assays*
**作者**：Kim, S., et al.
**摘要**：研究利用RPS23 (N-term)抗体阻断实验，证明RPS23通过N端结构域直接结合RNA病毒基因组，调控宿主天然免疫应答。该抗体在病毒感染细胞模型中有效抑制了病毒复制，提示RPS23可作为抗病毒治疗的潜在靶点。
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如需具体文献，建议通过**PubMed**或**Google Scholar**以关键词“RPS23 antibody N-terminal”检索，并筛选涉及抗体开发、验证或功能研究的文章。
The RPS23 (N-term) antibody is a specialized tool designed to target the N-terminal region of the Ribosomal Protein S23 (RPS23), a critical component of the 40S ribosomal subunit. RPS23 plays an essential role in mRNA translation and ribosome biogenesis, contributing to the structural stability of the ribosome and ensuring proper protein synthesis. This antibody is commonly used in research to study ribosomal function, cellular stress responses, and diseases linked to translational dysregulation, such as cancer or genetic disorders like Diamond-Blackfan anemia.
Developed through immunization with synthetic peptides or recombinant proteins corresponding to the N-terminal sequence of RPS23. the antibody is validated for applications like Western blotting, immunofluorescence, and immunoprecipitation. Its specificity for the N-terminal domain allows researchers to distinguish RPS23 from potential isoforms or degradation products. Many commercial RPS23 (N-term) antibodies are raised in hosts like rabbits or mice and undergo rigorous testing (e.g., knockout validation) to confirm minimal cross-reactivity. Researchers also use it to explore RPS23's non-ribosomal roles, including interactions with viral RNA or involvement in signaling pathways. Its utility extends to both basic molecular studies and clinical investigations, making it a versatile reagent for understanding ribosome-related mechanisms in health and disease.
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