| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Receptor expression-enhancing protein 5, Polyposis locus protein 1, Protein TB2, REEP5, C5orf18, DP1, TB2 |
| Entrez GeneID | 7905 |
| WB Predicted band size | 21.5kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This REEP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-169 amino acids from the C-terminal region of human REEP5. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于REEP5抗体的参考文献示例(内容基于学术文献常见主题构造，非真实文献)：
1. **文献名称**：*REEP5 modulates endoplasmic reticulum-mitochondria contacts and apoptosis signaling*
**作者**：Chen L et al.
**摘要**：研究利用REEP5抗体通过免疫荧光和Western blot发现REEP5调控内质网-线粒体接触位点，影响细胞凋亡通路，为相关疾病治疗提供新靶点。
2. **文献名称**：*REEP5 deficiency exacerbates cardiac hypertrophy via dysregulated sarco/endoplasmic reticulum calcium ATPase activity*
**作者**：Wang Y et al.
**摘要**：通过REEP5抗体检测基因敲除小鼠模型，揭示REEP5缺失通过干扰钙离子稳态加剧心肌肥大，提示其在心血管疾病中的保护作用。
3. **文献名称**：*REEP5 expression correlates with hepatocellular carcinoma progression and predicts poor prognosis*
**作者**：Tanaka K et al.
**摘要**：使用REEP5抗体进行免疫组化分析，发现肝癌组织中REEP5表达异常升高，与肿瘤侵袭性和患者预后不良显著相关。
4. **文献名称**：*REEP5 interacts with tau protein and influences its aggregation in Alzheimer’s disease models*
**作者**：Smith J et al.
**摘要**：研究通过REEP5抗体共沉淀实验，证实REEP5与tau蛋白互作，调控其异常聚集，为阿尔茨海默病机制提供新见解。
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注：以上文献为示例性质，实际引用需以真实发表的论文为准。建议通过PubMed或Google Scholar检索关键词“REEP5 antibody”获取最新研究。
The REEP5 (Receptor Expression-Enhancing Protein 5) antibody is a tool used to study the REEP5 protein, a member of the REEP family (REEP1-6) involved in endoplasmic reticulum (ER) membrane remodeling, protein trafficking, and lipid metabolism. REEP5. also known as DP1. is enriched in the ER and plays roles in shaping ER tubules, facilitating vesicle transport, and maintaining ER-mitochondria contact sites. It interacts with microtubules and membrane proteins, influencing secretory pathways and neuronal function. Dysregulation of REEP5 has been implicated in metabolic disorders, neurodegenerative diseases, and cancer.
The REEP5 antibody is essential for detecting and quantifying REEP5 expression in tissues or cells via techniques like Western blotting, immunofluorescence, or immunohistochemistry. It aids in exploring REEP5’s involvement in cellular stress responses, lipid homeostasis, and disease mechanisms. Researchers validate its specificity through knockout controls or siRNA-mediated knockdown. Commercial REEP5 antibodies are typically raised in rabbits or mice, targeting specific epitopes (e.g., C-terminal regions). Proper validation ensures reliable results in studying REEP5’s biological functions and its potential as a therapeutic or diagnostic target.
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