| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | PRELI domain-containing protein 1, mitochondrial, 25 kDa protein of relevant evolutionary and lymphoid interest, Px19-like protein, PRELID1, PRELI |
| Entrez GeneID | 27166 |
| WB Predicted band size | 25.2kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This PRELID1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-54 amino acids from the N-terminal region of human PRELID1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
+ +
以下是关于PRELID1 (N-term)抗体的3篇参考文献示例(注：文献信息为模拟示例，实际引用需核实原文)：
---
1. **文献名称**：*PRELID1 regulates mitochondrial apoptotic signaling in leukemia cells*
**作者**：Suzuki, M. et al.
**摘要**：本研究利用PRELID1 (N-term)抗体通过Western blot和免疫荧光技术，证实PRELID1在急性髓系白血病细胞中高表达，并调控线粒体途径的凋亡信号，影响Bax/Bak依赖性细胞色素c释放。
2. **文献名称**：*Interactions of PRELI domain proteins in mitochondrial membrane dynamics*
**作者**：Tait, S.W. et al.
**摘要**：通过免疫共沉淀(使用PRELID1 N端抗体)，揭示了PRELID1与SLMO2等线粒体蛋白形成复合物，参与维持线粒体膜结构及ROS稳态，为线粒体分裂机制提供新见解。
3. **文献名称**：*PRELID1 modulates cellular metabolism via lipid transfer activity*
**作者**：Takeda, K. et al.
**摘要**：该研究使用PRELID1 (N-term)抗体进行组织特异性敲除实验，发现PRELID1通过转运磷脂酸影响线粒体能量代谢，其缺失导致肝癌细胞中ATP合成显著下降。
---
**注意**：以上文献信息为基于领域知识的模拟生成，实际引用需通过PubMed、Google Scholar或抗体供应商(如CST、Abcam)的引用列表核实。建议通过关键词“PRELID1 antibody N-terminal”或抗体货号检索具体文献。
The PRELID1 (N-term) antibody is designed to target the N-terminal region of PRELID1 (PRELI Domain-Containing Protein 1), a member of the evolutionarily conserved PRELI family. PRELID1 is primarily localized to mitochondria and plays a critical role in regulating mitochondrial homeostasis, including lipid transport, apoptosis, and cellular metabolism. It interacts with TRIAP1 (TP53-regulated inhibitor of apoptosis 1) to form a complex involved in maintaining mitochondrial membrane integrity and modulating the balance of reactive oxygen species (ROS). Dysregulation of PRELID1 has been implicated in cancer, neurodegenerative disorders, and metabolic diseases, highlighting its importance in cellular survival and stress responses.
The PRELID1 (N-term) antibody is commonly used in research applications such as Western blotting, immunofluorescence, and immunoprecipitation to detect endogenous PRELID1 protein levels. Its specificity for the N-terminal epitope ensures minimal cross-reactivity with other PRELI family members, making it a reliable tool for studying PRELID1's distinct functions. Researchers employ this antibody to investigate PRELID1's role in mitochondrial dynamics, apoptosis signaling, and its potential as a therapeutic target in diseases linked to mitochondrial dysfunction. Validation typically includes knockout controls or siRNA-mediated silencing to confirm target specificity. Commercial sources often provide detailed data on its performance in various cell lines and tissues, supporting its utility in both basic and translational studies.
×
