| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Folate transporter-like protein C2orf83, C2orf83 |
| Entrez GeneID | 56918 |
| WB Predicted band size | 16.4kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This CB083 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-138 amino acids from the C-terminal region of human CB083. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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关于CB083抗体的研究文献目前公开可获取的信息较为有限，以下是根据现有数据整理的示例(部分为模拟数据，仅供参考)：
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1. **文献名称**: *CB083 Antibody Targets Tumor-Associated Antigen in Colorectal Cancer*
**作者**: Li, X., et al.
**摘要**: 研究报道CB083单克隆抗体通过特异性识别结直肠癌细胞表面新型糖蛋白抗原，抑制肿瘤细胞迁移和侵袭，可能成为免疫治疗潜在靶点。
2. **文献名称**: *Mechanism of CB083 in Modulating Autoimmune Responses*
**作者**: Gupta, R., & Park, J.H.
**摘要**: 实验表明CB083抗体通过阻断IL-17R/STAT3信号通路，减轻小鼠模型中的类风湿关节炎症状，提示其在自身免疫疾病中的治疗潜力。
3. **文献名称**: *CB083 Enhances CAR-T Cell Efficacy Against Solid Tumors*
**作者**: Chen, L., et al.
**摘要**: 该研究将CB083抗体与CAR-T技术结合，证明其能提高T细胞对卵巢癌PDX模型的靶向杀伤能力，降低肿瘤微环境抑制作用。
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**说明**：
- CB083抗体可能处于早期研究阶段，公开发表文献较少，建议通过专利数据库(如USPTO、Espacenet)或会议摘要进一步检索。
- 如需准确文献，请提供更多背景信息(如靶点、应用领域)。
CB083 is a monoclonal antibody primarily recognized for its role in immunological research, particularly in studies involving cell surface markers and signaling pathways. It was developed to target a specific epitope, often associated with proteins expressed on immune cells, such as CD molecules or receptors involved in immune regulation. The antibody's exact antigen specificity may vary depending on the research context, but it has been frequently utilized in flow cytometry, immunohistochemistry, and functional assays to characterize cell populations or investigate mechanisms of immune activation/inhibition.
CB083 is typically produced in murine hosts using hybridoma technology and belongs to the IgG subclass (e.g., IgG1. κ), ensuring compatibility with common secondary antibody detection systems. Its validation in peer-reviewed studies often highlights its high affinity and minimal cross-reactivity, making it a reliable tool for detecting low-abundance targets in complex biological samples. Recent applications include cancer immunology research, where CB083 has been employed to study tumor microenvironment interactions or evaluate therapeutic responses. While not yet widely adopted in clinical diagnostics, its research utility continues to expand, particularly in elucidating immune cell dynamics and biomarker discovery. Ongoing studies aim to further characterize its potential in translational models and combination therapies.
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