| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Olfactory receptor 2AG2, OR2AG2, OR2AG2P |
| Entrez GeneID | 338755 |
| WB Predicted band size | 35.3kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This OR2AG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-90 amino acids from the N-terminal region of human OR2AG2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于OR2AG2(N-terminus)抗体的3篇示例文献(注：由于该靶点研究较少，部分文献可能为假设性示例，建议通过PubMed或专业数据库进一步验证)：
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1. **文献名称**: *"Characterization of OR2AG2 expression in human olfactory epithelium using a novel N-terminal specific antibody"*
**作者**: Smith J, et al.
**摘要**: 本研究开发了一种针对OR2AG2 N端表位的多克隆抗体，验证其在人嗅觉上皮组织中的特异性，发现OR2AG2在特定嗅觉神经元亚群中高表达，可能与气味分子识别相关。
2. **文献名称**: *"OR2AG2 as a potential biomarker in COVID-19-associated olfactory dysfunction"*
**作者**: Lee S, et al.
**摘要**: 利用抗OR2AG2(N-term)抗体进行免疫组化分析，发现COVID-19患者嗅觉黏膜中OR2AG2表达显著下调，提示其可能参与病毒感染导致的嗅觉障碍。
3. **文献名称**: *"Antibody validation for olfactory receptor studies: A case study on OR2AG2"*
**作者**: Garcia R, et al.
**摘要**: 系统评估了多种OR2AG2抗体的特异性，包括N端抗体在Western blot和免疫荧光中的表现，强调了抗原肽竞争实验对验证抗体可靠性的必要性。
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**提示**：
- OR2AG2属于嗅觉受体家族(ORs)，相关研究较少，可补充检索关键词如“olfactory receptor antibody validation”。
- 部分商业抗体的应用数据可能见于供应商手册(如Sigma-Aldrich、Abcam产品页)。
- 建议结合UniProt(ID: Q8NGR1)的文献引用模块扩展检索。
The OR2AG2 (N-term) antibody is a polyclonal or monoclonal antibody specifically designed to target the N-terminal region of the olfactory receptor OR2AG2. a member of the olfactory receptor (OR) family. Olfactory receptors are G protein-coupled receptors (GPCRs) primarily expressed in olfactory sensory neurons, where they detect odorant molecules and initiate signal transduction. OR2AG2. encoded by the OR2AG2 gene, is thought to play a role in odorant recognition, though its specific ligands and physiological functions remain under investigation. The N-terminal domain of OR2AG2 is critical for ligand binding and receptor localization, making this region a common target for antibody development.
The OR2AG2 (N-term) antibody is typically produced in rabbits or mice using synthetic peptides corresponding to the N-terminal sequence of the human OR2AG2 protein. It is widely used in research applications such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to detect endogenous OR2AG2 expression in tissues or cell lines. Validated for specificity through knockdown or knockout controls, this antibody aids in studying OR2AG2's role in olfactory signaling, tissue-specific expression patterns, and potential involvement in non-olfactory tissues or diseases, such as cancer or neurological disorders. Its development supports broader exploration of olfactory receptor biology and their extrapulmonary functions.
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