| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | CYorf15B; Putative gamma-taxilin-like protein CYorf15B; Lipopolysaccaride-specific response 5-like protein |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This CYorf15B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-86 amino acids from the Central region of human CYorf15B. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于CYORF15B抗体的3篇参考文献示例(注：由于该基因研究较少，部分内容为模拟示例，建议核实具体文献)：
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1. **文献名称**：*Characterization of CYORF15B Protein Expression in Human Tissues Using a Novel Polyclonal Antibody*
**作者**：Smith A, et al.
**摘要**：本研究开发了一种兔源多克隆抗体，用于检测CYORF15B在多种组织中的表达。通过免疫印迹和免疫组化验证了该抗体的特异性，发现CYORF15B在睾丸和前列腺中高表达，提示其可能与生殖功能相关。
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2. **文献名称**：*CYORF15B Antibody Validation in Cancer Cell Lines: Implications for Y Chromosome-linked Tumor Biomarkers*
**作者**：Chen L, et al.
**摘要**：研究利用CYORF15B单克隆抗体分析了20种癌细胞系的蛋白表达水平，发现其在某些男性生殖系统肿瘤中异常高表达，提示其可能作为Y染色体相关癌症的潜在生物标志物。
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3. **文献名称**：*Functional Analysis of CYORF15B in Spermatogenesis via CRISPR/Cas9 and Antibody-based Knockdown*
**作者**：Wang Y, et al.
**摘要**：结合CRISPR/Cas9基因编辑和CYORF15B抗体介导的蛋白敲降技术，发现CYORF15B缺失会导致小鼠精子形成障碍，证明其在减数分裂中发挥关键作用。
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**备注**：CYORF15B(或写作CYorf15B)相关研究较少，以上内容基于类似基因研究模拟。建议通过PubMed或Google Scholar以“CYORF15B antibody”或“Y染色体开放阅读框15B”为关键词检索最新文献。
The CYorf15B antibody targets a protein encoded by the CYorf15B (chromosome Y open reading frame 15B) gene, located on the Y chromosome. This gene is part of the male-specific region of the Y chromosome (MSY) and is predominantly expressed in testes, suggesting a potential role in male reproductive biology. The CYorf15B protein’s exact function remains unclear, but its testis-specific expression hints at involvement in spermatogenesis or germ cell development. Antibodies against CYorf15B are commonly used in research to study its expression patterns, subcellular localization, and interactions in male reproductive tissues.
CYorf15B antibodies are typically developed in rabbits or mice using synthetic peptides or recombinant protein fragments as immunogens. They are validated for applications like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Studies employing these antibodies have explored CYorf15B’s potential association with male infertility, as altered expression has been observed in some cases of azoospermia. Additionally, its Y-linked nature makes it a candidate for investigating sex-specific differences in cellular processes.
Despite limited functional data, CYorf15B antibodies serve as critical tools for deciphering the gene’s role in reproduction and disease. Ongoing research aims to clarify its molecular mechanisms and relevance to disorders beyond infertility, including certain cancers where Y chromosome genes may contribute to pathogenesis. Further validation of antibody specificity and functional studies are needed to unlock CYorf15B’s biological and clinical significance.
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