| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Cell growth regulator with EF hand domain protein 1, Cell growth regulatory gene 11 protein, Hydrophobestin, CGREF1, CGR11 |
| Entrez GeneID | 10669 |
| WB Predicted band size | 33.5kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This CGREF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-292 amino acids from the C-terminal region of human CGREF1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于CGREF1抗体的3篇示例参考文献(注：以下为虚构内容，实际文献请通过PubMed或Google Scholar检索)：
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1. **文献名称**: *CGREF1 regulates neuronal development through synaptic adhesion pathways*
**作者**: Li X, Zhang Y, et al.
**摘要**: 本研究利用CGREF1特异性抗体，通过免疫荧光和Western blot技术，发现CGREF1在小鼠海马神经元突触形成中高表达。抗体阻断实验表明，CGREF1通过调控钙信号通路影响突触可塑性，提示其在神经发育中的关键作用。
2. **文献名称**: *CGREF1 as a novel biomarker in non-small cell lung cancer: Validation by immunohistochemical analysis*
**作者**: Tanaka K, Watanabe T, et al.
**摘要**: 研究通过开发高特异性CGREF1单克隆抗体，证实CGREF1在肺癌组织中的异常高表达。免疫组化结果显示，CGREF1水平与患者预后不良相关，提示其作为潜在治疗靶点的价值。
3. **文献名称**: *Functional characterization of CGREF1 in embryonic stem cell differentiation*
**作者**: Chen L, Zhou M, et al.
**摘要**: 通过CGREF1抗体介导的蛋白质定位和敲低实验，揭示CGREF1通过调控Wnt/β-catenin信号通路参与胚胎干细胞的自我更新和分化，为干细胞治疗提供新机制。
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如需真实文献，建议检索关键词“CGREF1 antibody”、“CGREF1 function”或结合具体研究领域(如癌症、神经科学)进行筛选。
The CGREF1 (Cellular Growth Regulation with EF-hand domain 1) antibody is a tool used to study the CGREF1 protein, which is encoded by the CGREF1 gene. This protein is characterized by an EF-hand calcium-binding domain, suggesting potential involvement in calcium-mediated signaling pathways. CGREF1 is evolutionarily conserved and ubiquitously expressed across tissues, with higher levels observed in the brain, kidneys, and testes. Though its precise biological function remains under investigation, studies link CGREF1 to cellular processes such as proliferation, differentiation, and apoptosis. It has been implicated in neural development, tumor suppression, and stress responses, with altered expression reported in certain cancers and neurodegenerative disorders.
The CGREF1 antibody is primarily utilized in research applications like Western blotting, immunohistochemistry, and immunofluorescence to detect protein expression, localization, and interaction partners. Its development has facilitated exploration of CGREF1's role in disease mechanisms, particularly in cancer biology and neurological conditions. However, further studies are needed to clarify its molecular pathways and validate its potential as a diagnostic or therapeutic target. Commercial CGREF1 antibodies are typically validated for specificity using knockout controls or siRNA-mediated silencing to ensure reliability in experimental settings.
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