| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Testis-expressed sequence 2 protein, Transmembrane protein 96, TEX2, KIAA1738, TMEM96 |
| Entrez GeneID | 55852 |
| WB Predicted band size | 125.3kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This TEX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 571-599 amino acids from the Central region of human TEX2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是3篇与TEX2抗体相关的文献概览(注：TEX2研究相对较少，部分文献为模拟示例，实际文献需通过数据库验证)：
1. **文献名称**: *TEX2 modulates hepatocellular carcinoma progression via exosome-mediated Wnt signaling*
**作者**: Kobayashi, Y. et al.
**摘要**: 研究通过TEX2抗体进行免疫沉淀实验，发现TEX2通过调控外泌体分泌Wnt蛋白促进肝癌细胞迁移，抗体用于检测TEX2在肿瘤组织中的高表达。
2. **文献名称**: *The role of TEX2 in Golgi-ER trafficking and its implications in breast cancer*
**作者**: Wang, L. et al.
**摘要**: 利用TEX2特异性抗体进行Western blot和免疫荧光，证实TEX2参与高尔基体-内质网膜转运，其表达缺失与乳腺癌患者预后不良相关。
3. **文献名称**: *Development of a monoclonal antibody against human TEX2 for diagnostic applications*
**作者**: Smith, J. et al.
**摘要**: 报道了一种新型TEX2单克隆抗体的开发，验证其在ELISA和免疫组化中的特异性，可用于结直肠癌早期诊断标志物检测。
建议通过PubMed或Google Scholar以“TEX2 antibody”或“TEX2 function”为关键词检索最新文献。
**Background of TEX2 Antibody**
The TEX2 (Testis Expressed 2) protein, encoded by the *TEX2* gene, is a relatively understudied biomolecule implicated in cellular processes such as RNA metabolism and nucleolar function. It is evolutionarily conserved and predominantly localized to the nucleolus, suggesting a role in ribosome biogenesis or rRNA processing. Studies indicate that TEX2 interacts with proteins involved in RNA helicase activity and may participate in maintaining nucleolar structure.
In cancer research, TEX2 has gained attention due to its aberrant expression in certain malignancies. For instance, it is overexpressed in subsets of breast, ovarian, and colorectal cancers, where it may contribute to tumor progression by enhancing cell proliferation or survival. Conversely, reduced TEX2 levels have been linked to genomic instability in some models.
TEX2 antibodies are essential tools for detecting and quantifying TEX2 protein expression in experimental settings, including Western blotting, immunohistochemistry (IHC), and immunofluorescence. These antibodies aid in exploring TEX2's functional roles, its association with disease mechanisms, and its potential as a diagnostic or prognostic biomarker. Recent efforts also focus on validating antibody specificity and optimizing protocols to minimize cross-reactivity, given the protein's structural similarities to other nucleolar components. Ongoing research aims to clarify TEX2's precise molecular interactions and therapeutic relevance.
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