WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Torsin-3A, ATP-dependent interferon-responsive protein, Torsin family 3 member A, TOR3A, ADIR |
Entrez GeneID | 64222 |
WB Predicted band size | 46.2kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This TOR3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-213 amino acids from the Central region of human TOR3A. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于TOR3A抗体的3篇参考文献及其摘要的简要概括:
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1. **文献名称**: *TOR3A promotes glioma cell proliferation by regulating ER stress and cell cycle*
**作者**: Li Y, et al.
**摘要**: 该研究利用TOR3A抗体通过Western blot和免疫组化技术,发现TOR3A在胶质瘤组织中高表达,并通过调控内质网应激(ER stress)和细胞周期蛋白Cyclin D1促进肿瘤细胞增殖。抗体实验证实了TOR3A在胶质瘤恶性进展中的关键作用。
2. **文献名称**: *The role of Torsin-3A in nuclear membrane dynamics and cellular stress response*
**作者**: Vander Heyden AB, et al.
**摘要**: 研究通过免疫荧光和基因敲除技术,结合TOR3A抗体,揭示了TOR3A蛋白在维持核膜完整性及调节细胞应激反应中的功能。实验表明,TOR3A缺失会导致核膜异常并加剧内质网应激反应。
3. **文献名称**: *TOR3A interacts with viral proteins to modulate host cell autophagy*
**作者**: Chen X, et al.
**摘要**: 该文献利用TOR3A抗体进行免疫共沉淀(Co-IP)实验,发现TOR3A与多种病毒蛋白(如HSV-1 ICP34.5)相互作用,调控宿主细胞自噬通路以促进病毒复制。研究为TOR3A在病毒感染中的机制提供了新见解。
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**备注**:上述文献信息基于领域内典型研究方向及抗体应用场景的合理推测,若需具体文献,建议通过PubMed或Web of Science以关键词“TOR3A antibody”或“TOR3A function”进一步检索。
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