| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Long-chain fatty acid transport protein 1, FATP-1, Fatty acid transport protein 1, 621-, Solute carrier family 27 member 1, SLC27A1, ACSVL5, FATP1 |
| Entrez GeneID | 376497 |
| WB Predicted band size | 71.1kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This SLC27A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 583-612 amino acids from the C-terminal region of human SLC27A1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是3篇关于SLC27A1抗体的文献示例(内容为模拟，实际文献需通过数据库检索)：
1. **文献名称**：*SLC27A1/FATP1 expression in adipose tissue regulates fatty acid transport in obesity*
**作者**：Smith, J. et al.
**摘要**：研究通过SLC27A1特异性抗体检测肥胖小鼠脂肪组织中该蛋白的表达水平，发现其上调与脂肪酸摄取增加相关，提示其在代谢紊乱中的作用。
2. **文献名称**：*Role of SLC27A1 in hepatocellular carcinoma progression revealed by immunohistochemical analysis*
**作者**：Chen, L. et al.
**摘要**：利用抗SLC27A1抗体进行肝癌组织染色，发现高表达SLC27A1与肿瘤细胞脂质代谢异常及患者预后不良显著相关。
3. **文献名称**：*Development and validation of a monoclonal antibody targeting human SLC27A1 for functional studies*
**作者**：Kim, S. et al.
**摘要**：报道一种新型SLC27A1单克隆抗体的开发，通过Western blot和免疫荧光验证其特异性，并用于探究SLC27A1在细胞膜定位中的功能。
(注：以上为示例，实际文献需通过PubMed/Google Scholar以关键词“SLC27A1 antibody”检索获取。)
SLC27A1. also known as fatty acid transport protein 1 (FATP1), is a membrane-associated protein that facilitates the uptake and metabolism of long-chain fatty acids. It plays a critical role in lipid homeostasis, energy production, and cellular signaling, with implications in metabolic disorders, cancer, and neurodegenerative diseases. Antibodies targeting SLC27A1 are essential tools for studying its expression, localization, and functional mechanisms in various tissues and disease models.
SLC27A1 antibodies are typically developed using immunogenic peptide sequences or recombinant protein fragments derived from conserved regions of the human or murine SLC27A1 protein. These antibodies may be polyclonal or monoclonal, with validation methods including Western blotting (WB), immunohistochemistry (IHC), immunofluorescence (IF), and flow cytometry. High-quality antibodies should demonstrate specificity through knockout cell line validation or competitive inhibition assays to avoid cross-reactivity with other SLC27A isoforms (e.g., SLC27A2-A6).
Research applications of SLC27A1 antibodies include investigating lipid metabolism dysregulation in obesity, diabetes, and non-alcoholic fatty liver disease (NAFLD), as well as exploring its oncogenic or tumor-suppressive roles in specific cancers. Commercial SLC27A1 antibodies are available from multiple suppliers, often accompanied by detailed protocols and species reactivity data (e.g., human, mouse, rat). Proper optimization of antibody dilution and detection conditions is crucial for reliable results due to variable expression levels across tissues.
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