关键信息
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基因名
BEND6
- 应用
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别名
BEND6；C6orf65；BEN domain-containing Protein 6
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5SZJ8
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表达区间
1-279aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMQKIVQT DEITNTQAFR KGKRKRTETM DSENANSDMD KGQRDPYSGN AFLPGESSSE DEEPLAELSK EELCAKIKSL KEKLTNTRKE NSRLRQSLVM LQVLPQAVTQ FEELVGMAEA LLKGGGTMST SASTLWRATN NSSPDSFAST CSNSNSNSSS PVSLKPEEEH QTDEKQFQIE KWQIARCNKS KPQKFINDLM QVLYTNEYMA THSLTGAKSS TSRDKAVKPA MNQNEVQEII GVTKQLFPNT DDVSIRRMIG QKLNNCTKKP NLSKNLNSQD IK
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分子量
34 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
BEND6, a member of the BEND (bromodomain and extra-terminal domain) family of proteins, has garnered significant attention in recent research due to its potential roles in gene regulation and chromatin remodeling. This protein is characterized by the presence of multiple protein interaction domains, which suggest that it may participate in various cellular processes, including transcriptional regulation and signal transduction. Studies have indicated that BEND6 is involved in developmental pathways and may contribute to oncogenesis when dysregulated. With its implications in critical biological mechanisms, understanding the structure, function, and regulatory networks involving BEND6 can provide insights into its role in health and disease. Recent advancements in proteomic techniques and molecular biology have facilitated the exploration of BEND6's interactions with other proteins and its influence on the epigenetic landscape, highlighting its potential as a therapeutic target in cancer and other disorders linked to gene misregulation. As research continues, elucidating the precise functions and mechanisms of BEND6 will be pivotal in uncovering its contributions to cellular homeostasis and disease pathology.
