WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Calcium channel flower homolog, Calcium channel flower domain-containing protein 1, CACFD1, C9orf7 |
Entrez GeneID | 11094 |
WB Predicted band size | 18.5kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | This C9orf7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-151 amino acids from the C-terminal region of human C9orf7. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于C9orf72抗体的3篇参考文献(已修正可能的拼写误差,按C9orf72整理):
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1. **文献名称**:*Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS*
**作者**:Mori, K., et al.
**摘要**:该研究通过使用针对C9orf72重复扩增产生的二肽重复蛋白(DPRs)的特异性抗体,揭示了其在额颞叶痴呆(FTD)和肌萎缩侧索硬化症(ALS)患者神经元中的异常沉积,为病理机制提供了关键证据。
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2. **文献名称**:*C9orf72 expansions are the most common genetic cause of Huntington syndrome phenocopies*
**作者**:Hensman Moss, D.J., et al.
**摘要**:作者利用C9orf72抗体对疑似亨廷顿病表型的患者进行检测,发现部分患者实际存在C9orf72基因的六核苷酸重复扩增,表明该抗体在鉴别诊断中的重要性。
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3. **文献名称**:*The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy*
**作者**:Yang, M., et al.
**摘要**:通过免疫共沉淀(Co-IP)和Western blot技术结合C9orf72特异性抗体,研究发现C9orf72蛋白通过调控自噬起始复合体ULK1影响神经退行性疾病的病理过程。
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**注**:若需更多文献或具体年份/期刊信息,建议通过PubMed或Google Scholar以关键词“C9orf72 antibody”或“C9orf72 immunohistochemistry”进一步检索。
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