| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Actin-like protein 9, ACTL9, ACTL7C |
| Entrez GeneID | 284382 |
| WB Predicted band size | 45.6kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This ACTL9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-50 amino acids from the N-terminal region of human ACTL9. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于ACTL9 (N-term)抗体的3篇参考文献的简要整理(基于公开数据模拟，可能非真实存在)：
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1. **文献名称**: "Characterization of ACTL9 Antibody Specificity in Sperm Formation"
**作者**: Smith J, et al.
**摘要**: 本研究验证了针对ACTL9蛋白N端的多克隆抗体的特异性，发现其在小鼠精子形成过程中特异性标记ACTL9蛋白的表达，并揭示了其在精子顶体发育中的潜在调控作用。
2. **文献名称**: "ACTL9 Interaction with Cytoskeletal Proteins Revealed by Immunoprecipitation"
**作者**: Chen L, et al.
**摘要**: 通过使用ACTL9 (N-term)抗体进行免疫共沉淀实验，作者发现ACTL9与细胞骨架蛋白ARP2/3复合物存在相互作用，提示其在细胞运动中的功能。
3. **文献名称**: "ACTL9 as a Biomarker in Ovarian Cancer: Antibody Validation Study"
**作者**: Wang Y, et al.
**摘要**: 研究通过Western blot和免疫组化验证了ACTL9 N端抗体的可靠性，发现卵巢癌组织中ACTL9表达显著上调，可能成为潜在诊断标志物。
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注：以上文献为模拟示例，若需真实文献，建议通过PubMed或Google Scholar搜索关键词“ACTL9 antibody”或联系抗体供应商(如Abcam、Santa Cruz等)获取引用资料。
The ACTL9 (N-term) antibody is a specialized immunological tool designed to target the N-terminal region of the Actin-like protein 9 (ACTL9). ACTL9 belongs to the actin-related protein (ARP) family, which shares structural homology with conventional actins but has evolved distinct roles in cellular processes. While actins are primarily involved in cytoskeletal dynamics, ACTL9 is implicated in more specialized functions, potentially linked to chromatin remodeling complexes or acrosomal formation during spermatogenesis, as suggested by studies in model organisms.
The N-terminal region of ACTL9 is often targeted by antibodies due to its relative conservation and unique epitope availability compared to other actin-like proteins, enabling specific detection. This antibody is commonly used in techniques like Western blotting, immunofluorescence, and immunoprecipitation to study ACTL9 expression, localization, and interactions in various biological samples. Its development typically involves immunizing host animals (e.g., rabbits or mice) with synthetic peptides or recombinant protein fragments corresponding to the N-terminal sequence.
Researchers utilize this antibody to investigate ACTL9's potential roles in cellular processes such as meiosis, transcriptional regulation, and structural organization. Its validation often includes knockout cell line controls or tissue-specific expression patterns. Commercial versions may vary in clonality (monoclonal/polyclonal), species reactivity, and application-specific validation, requiring careful selection based on experimental needs.
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