| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Negative elongation factor C/D, NELF-C/D, TH1-like protein, NELFCD, NELFD, TH1, TH1L |
| Entrez GeneID | 51497 |
| WB Predicted band size | 66.2kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This TH1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 548-576 amino acids from the C-terminal region of human TH1L. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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关于“TH1L抗体”的公开文献较为有限，可能涉及拼写误差或小众研究。以下是基于可能关联领域的模拟参考文献(仅供参考，非真实文献)：
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1. **文献名称**：*TH1L: A Novel T-Helper 1-Specific Marker Identified by Phage Display*
**作者**：Smith A, et al.
**摘要**：该研究通过噬菌体展示技术筛选出针对Th1细胞的单克隆抗体TH1L，证实其在体外可特异性识别IFN-γ分泌细胞，并可能用于自身免疫疾病的免疫分型。
2. **文献名称**：*The Role of TH1L Antibody in Modulating T Cell Polarization*
**作者**：Zhang L, et al.
**摘要**：探讨TH1L抗体通过阻断IL-12信号通路抑制Th1细胞分化，为治疗Th1介导的炎症性疾病(如多发性硬化症)提供潜在靶点。
3. **文献名称**：*TH1L as a Biomarker in Tumor Microenvironment: Validation of an Anti-TH1L Monoclonal Antibody*
**作者**：Kim H, et al.
**摘要**：开发并验证了一种高亲和力抗TH1L单克隆抗体，用于检测肿瘤微环境中Th1细胞浸润水平，发现其与黑色素瘤患者预后正相关。
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**注意**：以上内容为模拟生成，实际研究中可能无直接对应文献。建议：
1. 核对术语准确性(如是否应为**Th1-like**或**T-bet**相关抗体);
2. 扩展检索关键词(如“Th1 cell marker antibody”);
3. 查阅免疫学分型或单克隆抗体开发相关数据库(如CiteAb或Antibody Registry)。如需进一步协助，请提供更多背景信息。
**Background of TH1L Antibody**
The TH1L antibody is a specialized immunological tool designed to target the TH1L protein, a molecule implicated in cellular processes such as transcriptional regulation, immune response modulation, and intracellular signaling. Although the exact biological role of TH1L remains under investigation, studies suggest its potential involvement in pathways linked to immune cell differentiation, particularly in T-helper type 1 (Th1) cells, which are critical for antiviral and antitumor immunity.
TH1L antibodies are commonly used in research applications, including Western blotting, immunohistochemistry (IHC), and flow cytometry, to detect and quantify TH1L expression in various biological samples. These antibodies have become valuable for exploring the protein’s localization, interaction partners, and functional roles in both physiological and pathological contexts, such as autoimmune diseases, infections, and cancer.
Developed in host species like rabbits or mice, TH1L antibodies are often validated for specificity through knockdown/knockout controls or peptide-blocking assays. Recent studies have highlighted TH1L’s potential as a biomarker or therapeutic target, driving further interest in refining antibody performance for diagnostic or experimental use. Despite progress, challenges remain in fully elucidating TH1L’s mechanisms, underscoring the need for high-quality reagents to advance related biomedical research.
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