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Rabbit Polyclonal GFOD2(N-term) Antibody

  • 中文名: GFOD2 (N-term)抗体
  • 别    名: Glucose-fructose oxidoreductase domain-containing protein 2, 1---, GFOD2
货号: IPDX31745
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 1/1000 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesGlucose-fructose oxidoreductase domain-containing protein 2, 1---, GFOD2
Entrez GeneID81577
WB Predicted band size42.3kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenThis GFOD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-305 amino acids from the N-terminal region of human GFOD2.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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参考文献

以下是关于GFOD2 (N-term)抗体的虚构参考文献示例(仅供格式参考,实际文献需通过学术数据库查询):

1. **"Characterization of GFOD2 N-terminal antibody in pancreatic cancer models"**

*Authors: Lee, J. et al.*

摘要:本研究利用GFOD2 (N-term)抗体检测了胰腺癌细胞中GFOD2蛋白的N端表达,发现其在糖代谢调控中起关键作用,并通过免疫组化证实了其与肿瘤进展的相关性。

2. **"Development of a polyclonal antibody targeting the N-terminal domain of GFOD2"**

*Authors: Martinez, R. et al.*

摘要:文章报道了一种新型GFOD2 N端多克隆抗体的制备与验证,通过Western blot和免疫荧光验证其特异性,并用于研究GFOD2在小鼠肝脏组织中的表达模式。

3. **"GFOD2-mediated fructose metabolism in diabetic nephropathy: Insights from antibody-based assays"**

*Authors: Chen, X. et al.*

摘要:利用GFOD2 (N-term)抗体揭示GFOD2在糖尿病肾病模型中的表达上调,通过免疫沉淀技术发现其与果糖代谢酶相互作用,提示潜在治疗靶点。

**备注**:以上为示例性内容,实际文献需通过PubMed、Web of Science等平台检索。建议尝试关键词:`"GFOD2" AND ("antibody" OR "N-terminal")`,或查阅抗体供应商(如Abcam、Sigma)的产品引用文献列表。

背景信息

The GFOD2 (N-term) antibody is designed to detect the N-terminal region of GFOD2 (Glycolate oxidase domain-containing protein 2), a protein encoded by the GFOD2 gene in humans. GFOD2 is part of the FAD-linked oxidoreductase family and contains a glycolate oxidase domain, suggesting potential roles in redox reactions or metabolic pathways. While its precise biological function remains under investigation, GFOD2 is hypothesized to participate in cellular processes involving small molecule metabolism, possibly linking it to energy homeostasis or detoxification pathways. The protein is expressed in various tissues, with higher levels observed in the liver, kidney, and brain, implying tissue-specific roles.

The N-terminal region targeted by this antibody likely contains critical structural or functional motifs, making it valuable for studying protein localization, expression patterns, or post-translational modifications. Researchers utilize this antibody in applications such as Western blotting, immunohistochemistry, and immunofluorescence to investigate GFOD2's role in physiological and pathological contexts, including metabolic disorders, neurodegenerative diseases, or cancer. Validation typically includes specificity tests using knockout controls or tagged recombinant proteins. As GFOD2 remains relatively understudied compared to other family members, this antibody serves as a crucial tool for elucidating its molecular interactions and disease associations. Commercial versions often provide species reactivity (e.g., human, mouse, rat) and compatibility with multiple experimental platforms.

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