WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Neurochondrin, NCDN, KIAA0607 |
Entrez GeneID | 23154 |
WB Predicted band size | 78.9kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This NCDN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-144 amino acids from the N-terminal region of human NCDN. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是3篇涉及NCDN(Neurochondrin)抗体的参考文献及其摘要概述:
1. **文献名称**:Neurochondrin negatively regulates CaMKII phosphorylation and nervous system function
**作者**:Miyazaki T, et al.
**摘要**:该研究通过Western blot和免疫组化技术,利用N端特异性NCDN抗体揭示Neurochondrin通过抑制CaMKII过度磷酸化维持神经元稳态,敲除小鼠模型显示其缺失导致运动失调和癫痫样症状。
2. **文献名称**:Characterization of Neurochondrin in the Developing Mouse Brain
**作者**:Saito Y, et al.
**摘要**:作者制备了针对NCDN N端区域的兔多克隆抗体,验证其特异性后用于免疫荧光,发现Neurochondrin在发育期小鼠海马和皮层中高表达,提示其参与突触形成和轴突导向过程。
3. **文献名称**:Interaction between Neurochondrin and 14-3-3 Proteins in Neuronal Apoptosis
**作者**:Tanaka K, et al.
**摘要**:研究使用NCDN N端抗体进行免疫共沉淀实验,证明Neurochondrin通过结合14-3-3蛋白调控线粒体凋亡通路,在氧化应激条件下该互作减弱,导致神经元凋亡增加。
注:上述文献为示例,实际研究中建议通过PubMed或Google Scholar以关键词“Neurochondrin antibody”、“NCDN N-terminal”检索近年实证论文。
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