| WB | 1/500-1/8000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Ubiquitin-like protein 5, UBL5 |
| Entrez GeneID | 59286 |
| WB Predicted band size | 8.5kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Purified His-tagged UBL5 protein(Fragment) was used to produced this monoclonal antibody. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于UBL5(Ascites)抗体的示例参考文献(注：以下内容为模拟示例，实际文献需通过学术数据库检索确认)：
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1. **文献名称**: *UBL5 as a Novel Biomarker in Ovarian Cancer-Associated Ascites*
**作者**: Smith A, et al.
**摘要**: 本研究探讨了UBL5在卵巢癌腹水中的表达及其诊断价值。通过ELISA和Western blot分析，发现UBL5蛋白在腹水样本中显著高表达，提示其可能作为卵巢癌腹水的潜在生物标志物。
2. **文献名称**: *Role of UBL5 in Liver Cirrhosis-Related Ascites: Insights from Proteomic Profiling*
**作者**: Zhang L, et al.
**摘要**: 研究利用UBL5抗体对肝硬化患者腹水进行蛋白质组学分析，发现UBL5与炎症因子通路(如TNF-α/NF-κB)的调控相关，可能参与腹水形成的分子机制。
3. **文献名称**: *Development of a Monoclonal Antibody Against UBL5 for Ascites Fluid Detection*
**作者**: Johnson R, et al.
**摘要**: 本文报道了一种针对UBL5的单克隆抗体的开发，并验证其在肝癌患者腹水样本中的检测灵敏度和特异性。该抗体在临床诊断中显示出潜在应用价值。
4. **文献名称**: *UBL5-Mediated Stress Response Pathways in Ascites-Derived Cancer Cells*
**作者**: Lee H, et al.
**摘要**: 研究发现，UBL5通过调控内质网应激反应和细胞凋亡通路，影响腹水来源的肿瘤细胞存活能力，提示UBL5可能成为治疗恶性腹水的靶点。
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如需真实文献，建议使用关键词 **"UBL5" + "ascites" + "antibody"** 在 **PubMed**、**Google Scholar** 或 **Web of Science** 中检索。
The UBL5 (Ubiquitin-like 5) antibody is a tool used to study the UBL5 protein, a small ubiquitin-like modifier involved in diverse cellular processes. UBL5. also known as homologous to ubiquitin 1 (HUB1), lacks the C-terminal glycine residue required for classical ubiquitination but plays roles in pre-mRNA splicing, stress responses, and protein quality control. It interacts with spliceosomal components and regulates alternative splicing, particularly under stress conditions like heat shock or DNA damage.
The term "Ascites" in UBL5 (Ascites) antibody likely refers to its application in studying ascites-derived samples, such as those from cancer patients with malignant ascites (fluid accumulation in the abdomen). In cancers like ovarian or gastrointestinal malignancies, ascites often contains tumor cells and biomarkers. Researchers use this antibody to detect UBL5 expression in such contexts, exploring its potential role in tumor progression, metastasis, or stress adaptation. Elevated UBL5 levels in ascites-associated cancers may correlate with poor prognosis or drug resistance.
UBL5 antibodies are typically developed in rabbits or mice using immunogenic peptides. They enable techniques like Western blotting, immunohistochemistry, or immunofluorescence to localize and quantify UBL5 in tissues, cells, or fluid samples. Ongoing research aims to clarify UBL5's mechanistic contributions to disease and its utility as a diagnostic or therapeutic target.
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