关键信息
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基因名
AZGP1
- 应用
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别名
AZGP1；ZAG；ZNGP1；Zinc-alpha-2-glycoProtein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P25311
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表达区间
22-298aa
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氨基酸序列
ENQGGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDRKSQPM GLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRF GCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAE PVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKK KLKCLAYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVP PQDTAPYSCHVQHSSLAQPLVGPWEAS
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分子量
56 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
AZGP1 (alpha-2-glycoprotein 1, zinc-binding) is a glycoprotein that has garnered attention in scientific research due to its potential roles in various physiological and pathological processes. Initially identified as a protein that binds zinc, AZGP1 is predominantly expressed in adipose tissue and is implicated in lipid metabolism and energy regulation. Its expression levels are often altered in conditions such as obesity, diabetes, and cancer, leading to investigations into its functional significance. Researchers have discovered that AZGP1 may influence insulin sensitivity and adipocyte differentiation, suggesting its involvement in metabolic disorders. Additionally, studies have explored its potential as a biomarker for certain cancers, given its differential expression in tumor versus normal tissues. The recombinant production of AZGP1 has facilitated detailed biochemical and structural studies, allowing for a better understanding of its interactions and mechanisms of action. This research is crucial for developing therapeutic strategies targeting AZGP1 in metabolic diseases and cancer treatment, highlighting its importance in both basic and translational biomedical research.
