| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | RNA-binding protein 26, CTCL tumor antigen se70-2, RNA-binding motif protein 26, RBM26, C13orf10 |
| Entrez GeneID | 64062 |
| WB Predicted band size | 113.6kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This RBM26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-225 amino acids from the N-terminal region of human RBM26. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于RBM26 (N-term)抗体的参考文献示例(注：部分内容为假设性概括，实际文献需通过数据库验证)：
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1. **"RBM26 regulates alternative splicing in spermatogenesis"**
*Author: Zhang Y, et al. (2020)*
摘要：本研究利用RBM26 (N-term)抗体进行Western blot和免疫荧光实验，发现RBM26通过调控精子发生相关基因的可变剪接参与小鼠睾丸发育，抗体特异性验证显示其靶向N端表位。
2. **"RNA-binding motif protein 26 modulates cancer cell proliferation via mRNA stability"**
*Author: Lee S, et al. (2018)*
摘要：通过RBM26 (N-term)抗体的免疫沉淀和质谱分析，揭示RBM26与mRNA稳定性复合物相互作用，影响多种癌基因表达，研究证实其在乳腺癌细胞增殖中的调控作用。
3. **"Characterization of RBM26 protein interactions in neuronal RNA granules"**
*Author: Müller F, et al. (2019)*
摘要：使用RBM26 (N-term)抗体进行共聚焦显微镜和Co-IP实验，证明RBM26定位于神经元RNA颗粒，并与神经突触可塑性相关RNA结合蛋白存在功能关联。
4. **"Antibody validation for RBM26 in human tissue microarrays"**
*Author: Abcam Technical Note (2021)*
摘要：商业抗体说明书文献，验证了RBM26 (N-term)抗体在人类多种组织中的特异性，包括免疫组化及敲除细胞系的阴性对照实验，确认其适用于蛋白定位研究。
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**注意**：以上文献为示例性质，实际引用请通过PubMed、Google Scholar或抗体供应商官网(如[Abcam](https://www.abcam.com)、[Novus Biologicals](https://www.novusbio.com))检索关键词“RBM26 antibody N-terminal”获取真实参考文献。若研究较少，可扩展搜索RBM26功能研究的相关论文。
The RBM26 (N-term) antibody is a specialized tool designed to detect the N-terminal region of the RNA-binding motif protein 26 (RBM26), a member of the RNA-binding protein (RBP) family. RBM26 is implicated in RNA metabolism, including splicing, stabilization, and translation, by interacting with target RNAs through its conserved RNA-binding domains. The protein is ubiquitously expressed and plays roles in cellular processes such as transcriptional regulation, post-transcriptional modification, and stress response. Dysregulation of RBM26 has been linked to diseases, including cancers and neurological disorders, highlighting its biological relevance.
The N-terminal-specific antibody enables researchers to study RBM26’s expression, localization, and function in various tissues and experimental models. It is commonly used in techniques like Western blotting, immunohistochemistry (IHC), and immunoprecipitation (IP) to analyze protein levels, tissue distribution, and molecular interactions. Validated for specificity, this antibody helps distinguish RBM26 from homologous RBPs, ensuring accurate experimental outcomes. Its applications extend to investigating RBM26’s role in disease mechanisms, RNA-protein networks, and potential therapeutic targets. By targeting the N-terminal region, the antibody avoids interference with conserved RNA-binding domains, preserving functional epitopes for functional studies. This tool is essential for advancing research into RNA biology and RBM26-associated pathologies.
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