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Rabbit Polyclonal RPL9 Antibody

  • 中文名: RPL9抗体
  • 别    名: 60S ribosomal protein L9, RPL9
货号: IPDX31634
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 1/1000 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

Aliases60S ribosomal protein L9, RPL9
Entrez GeneID6133
WB Predicted band size21.9kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenThis RPL9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-177 amino acids from the C-terminal region of human RPL9.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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参考文献

以下是关于RPL9抗体的参考文献示例(内容为模拟,建议通过学术数据库核实具体文献):

1. **文献名称**:*"Characterization of a Polyclonal Antibody Against Human Ribosomal Protein L9"*

**作者**:Wang Y. et al.

**摘要**:该研究开发了一种针对人源RPL9的多克隆抗体,并通过Western blot和免疫荧光验证其特异性。实验表明该抗体适用于检测细胞裂解液及组织样本中的RPL9表达。

2. **文献名称**:*"RPL9 as a Novel Biomarker in Hepatocellular Carcinoma: Insights from Immunohistochemical Analysis"*

**作者**:Chen L. et al.

**摘要**:利用RPL9抗体对肝癌组织进行免疫组化染色,发现RPL9的高表达与肿瘤进展和患者生存率显著相关,提示其作为潜在诊断标志物的可能性。

3. **文献名称**:*"RPL9 Regulates p53 Activity by Modulating Ribosome Biogenesis in Response to DNA Damage"*

**作者**:Kim S. et al.

**摘要**:研究通过RPL9抗体进行免疫共沉淀和ChIP实验,揭示RPL9在DNA损伤后通过核糖体生物合成途径调控p53活性的分子机制。

4. **文献名称**:*"Validation of RPL9 Antibody for Flow Cytometry Applications in Immune Cell Profiling"*

**作者**:Müller R. et al.

**摘要**:验证了RPL9抗体在流式细胞术中的适用性,证明其可用于检测免疫细胞(如T细胞、巨噬细胞)中RPL9的亚细胞定位及表达水平变化。

建议通过PubMed或Google Scholar以“RPL9 antibody”为关键词检索最新文献获取具体信息。

背景信息

The RPL9 antibody is a research tool designed to detect Ribosomal Protein L9 (RPL9), a component of the 60S ribosomal subunit involved in protein synthesis. RPL9. encoded by the RPL9 gene in humans, plays a structural role in ribosome assembly and may participate in stabilizing rRNA interactions. Beyond its canonical role, emerging studies suggest RPL9 has extraribosomal functions, including potential involvement in cell cycle regulation, apoptosis, and DNA repair. Antibodies targeting RPL9 are widely used in techniques like Western blotting, immunofluorescence, and immunohistochemistry to study its expression, localization, and interactions in various tissues or cell lines. These antibodies are often validated for specificity across species, including human, mouse, and rat. Dysregulation of RPL9 has been observed in certain cancers, such as colorectal and breast cancer, linking its overexpression to tumor progression or chemoresistance. Researchers also utilize RPL9 antibodies to explore ribosomopathies and diseases linked to ribosomal dysfunction. Most commercial RPL9 antibodies are raised against conserved epitopes, typically using recombinant protein fragments or synthetic peptides as immunogens. Proper controls, like siRNA knockdown or knockout samples, are recommended to confirm antibody specificity in experimental settings.

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