| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Zinc finger protein 90, Zinc finger protein HTF9, ZNF90 |
| Entrez GeneID | 7643 |
| WB Predicted band size | 69.1kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This ZNF90 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-112 amino acids from the Central region of human ZNF90. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是几篇关于ZNF90抗体的示例参考文献(注：以下为假设性示例，实际文献需通过学术数据库验证)：
1. **文献名称**：*ZNF90 Antibody Characterization in Human Cell Lines*
**作者**：Smith J, et al.
**摘要**：本研究验证了ZNF90抗体的特异性，通过Western blot和免疫荧光证实其在多种人类细胞系中识别ZNF90蛋白，并探讨了其在基因表达调控中的作用。
2. **文献名称**：*Role of ZNF90 in Epigenetic Regulation: Insights from Antibody-Based Assays*
**作者**：Lee H, Kim S.
**摘要**：利用ZNF90抗体进行染色质免疫沉淀(ChIP)，揭示了ZNF90与特定DNA序列结合的能力，提示其在表观遗传修饰和癌症相关通路中的潜在功能。
3. **文献名称**：*ZNF90 Antibody Application in Neural Development Studies*
**作者**：Wang Y, et al.
**摘要**：通过免疫组化分析，发现ZNF90在哺乳动物神经发育过程中高表达，该抗体为研究锌指蛋白在神经元分化中的作用提供了工具。
4. **文献名称**：*Comparative Analysis of Commercial ZNF90 Antibodies*
**作者**：Garcia R, et al.
**摘要**：评估了不同厂商的ZNF90抗体的灵敏度和特异性，为研究者选择可靠试剂提供了实验依据，并强调抗体批次差异可能影响结果。
**建议**：实际文献请通过PubMed、Google Scholar或Web of Science搜索关键词(如"ZNF90 antibody" "ZNF90 zinc finger")，并优先选择近5年、高影响力期刊的研究。
The ZNF90 antibody is a research tool designed to target the zinc finger protein 90 (ZNF90), a member of the Krüppel-associated box (KRAB) domain-containing zinc finger protein family. ZNF90. encoded by the ZNF90 gene in humans, is characterized by multiple C2H2-type zinc finger motifs, which facilitate DNA binding and interaction with transcriptional co-regulators. These proteins are implicated in transcriptional regulation, chromatin remodeling, and cellular processes such as differentiation and apoptosis.
ZNF90 antibodies are typically developed using recombinant protein fragments or synthetic peptides corresponding to specific epitopes within the ZNF90 protein. They are widely employed in techniques like Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and chromatin immunoprecipitation (ChIP) to study ZNF90's expression patterns, subcellular localization, and functional roles in various tissues or disease contexts.
While the exact biological functions of ZNF90 remain under investigation, its structural similarity to other KRAB-ZNF proteins suggests potential involvement in gene silencing and transposable element repression. Research utilizing ZNF90 antibodies may explore its relevance in cancer, neurodevelopment, or immune regulation. However, challenges such as antibody specificity, cross-reactivity with homologous zinc finger proteins, and batch variability require rigorous validation via knockout controls or orthogonal assays. Commercial ZNF90 antibodies are available from multiple suppliers, but performance often varies, necessitating careful optimization for experimental consistency.
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