| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Olfactory receptor 4K13, Olfactory receptor OR14-27, OR4K13 |
| Entrez GeneID | 390433 |
| WB Predicted band size | 34.3kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This OR4K13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-93 amino acids from the N-terminal region of human OR4K13. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于OR4K13(N-term)抗体的假设性参考文献示例(仅供参考，实际文献需通过学术数据库验证)：
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1. **文献名称**：*"Characterization of Olfactory Receptor OR4K13 Expression in Human Olfactory Epithelium"*
**作者**：Smith et al., 2021
**摘要**：本研究利用OR4K13 N端特异性抗体，通过免疫组织化学技术证实了OR4K13在人类嗅觉上皮中的选择性表达，并揭示了其在嗅觉信号传导中的潜在作用。
2. **文献名称**：*"Development and Validation of Antibodies Targeting Olfactory Receptor N-terminal Domains"*
**作者**：Zhang et al., 2019
**摘要**：文章报道了一种针对OR4K13 N端表位的多克隆抗体的开发，经Western blot和免疫荧光验证，该抗体在HEK293细胞过表达模型及鼻腔组织样本中表现出高特异性。
3. **文献名称**：*"OR4K13 Localization and Function in Non-Olfactory Tissues"*
**作者**：Lee et al., 2020
**摘要**：通过N-term抗体研究发现，OR4K13在睾丸组织中异常表达，提示其可能参与嗅觉系统外的生理功能，如配子发生调控。
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**注意**：上述文献为示例，实际研究中OR4K13抗体相关文献可能较少。建议通过以下途径获取准确信息：
1. 检索PubMed或Google Scholar，关键词：**OR4K13 antibody N-term**。
2. 查阅抗体供应商(如Thermo Fisher、Abcam)的产品说明书，部分会附引用文献。
3. 关注嗅觉受体或GPCR研究领域的综述文章，或联系相关领域作者咨询。
The OR4K13 (N-term) antibody is a research tool designed to target the N-terminal region of the olfactory receptor family 4 subfamily K member 13 (OR4K13), a G protein-coupled receptor (GPCR) involved in olfactory signaling. Olfactory receptors (ORs) constitute the largest family of GPCRs, playing critical roles in detecting odorant molecules and initiating signal transduction pathways that translate chemical cues into neural signals. OR4K13 is part of the OR4K subfamily, which is characterized by its conserved seven-transmembrane domain structure and ligand-binding specificity. While ORs are predominantly expressed in olfactory sensory neurons, emerging studies suggest ectopic expression in non-olfactory tissues, implying potential roles in physiological processes beyond smell, such as cellular communication or disease pathways.
This antibody is commonly utilized in immunological assays, including Western blotting, immunohistochemistry, and immunofluorescence, to detect endogenous OR4K13 protein expression in experimental models. Its specificity for the N-terminal region ensures minimal cross-reactivity with other OR family members, aiding in precise localization and functional studies. Researchers employ it to explore OR4K13's tissue distribution, ligand interactions, or involvement in pathologies like anosmia or cancer. However, validation via knockout controls or peptide blocking is recommended due to the high sequence homology among ORs. Commercial sources often provide the antibody in purified forms (polyclonal or monoclonal), with host species typically being rabbit or mouse. Its application contributes to deciphering the complex olfactory code and OR-related mechanisms in health and disease.
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