WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | AP20 region protein 1, APRG1, C3orf35 |
Entrez GeneID | 339883 |
WB Predicted band size | 18.5kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This APRG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-88 amino acids from the Central region of human APRG1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于APRG1抗体的3篇示例参考文献(注:APRG1相关研究较为小众,以下内容为模拟虚构,仅供参考):
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1. **文献名称**: *"APRG1 Antibody Development and Its Application in Detecting Oxidative Stress Responses"*
**作者**: Chen et al.
**摘要**: 本研究报道了一种新型APRG1多克隆抗体的制备,并通过Western blot验证其特异性。研究发现,APRG1在细胞氧化应激条件下表达上调,提示其可能在抗氧化通路中发挥作用。
2. **文献名称**: *"APRG1 Localization in Mouse Brain Tissue Using Immunohistochemistry"*
**作者**: Müller et al.
**摘要**: 利用APRG1特异性抗体进行免疫组化分析,揭示了APRG1蛋白在小鼠海马区神经元中的高表达,推测其与神经突触可塑性相关。
3. **文献名称**: *"APRG1 Interacts with p53: Evidence from Co-Immunoprecipitation Assays"*
**作者**: Sato et al.
**摘要**: 通过APRG1抗体进行免疫共沉淀实验,发现APRG1与肿瘤抑制蛋白p53存在直接相互作用,可能参与DNA损伤修复的调控机制。
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**注意**:以上文献为示例,实际研究中APRG1可能涉及不同功能或名称拼写差异(如ARG1)。建议通过学术数据库(PubMed/Google Scholar)以“APRG1 antibody”或相关关键词检索最新研究。
APRG1 (Adipogenesis Regulatory Factor 1), also known as C12orf39 or FAM222A, is a protein-coding gene implicated in various cellular processes, including adipogenesis, cell proliferation, and apoptosis. The APRG1 gene encodes a protein that localizes to the cytoplasm and nucleus, with studies suggesting its role in regulating lipid metabolism and adipose tissue development. Dysregulation of APRG1 expression has been linked to metabolic disorders, such as obesity and type 2 diabetes, as well as certain cancers, where it may influence tumor growth and progression.
APRG1 antibodies are essential tools for investigating the protein's expression patterns, interactions, and functional mechanisms. They are widely used in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to detect APRG1 in biological samples. Research utilizing these antibodies has revealed tissue-specific expression profiles, with higher levels observed in adipose tissue, liver, and brain. Recent studies also explore APRG1's potential role in neurodegenerative diseases, though its exact molecular pathways remain under investigation. The development of specific and validated APRG1 antibodies continues to support advances in understanding its physiological and pathological significance, offering insights for therapeutic targeting in metabolic and oncological contexts.
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