WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Voltage-dependent L-type calcium channel subunit beta-1, CAB1, Calcium channel voltage-dependent subunit beta 1, CACNB1, CACNLB1 |
Entrez GeneID | 782 |
WB Predicted band size | 65.7kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This CACNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-572 amino acids from the C-terminal region of human CACNB1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是3篇涉及CACNB1抗体的文献摘要信息:
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**1. 文献名称**: *CACNB1 modulates conformational changes in CACNA1S to regulate calcium channel inactivation*
**作者**: Fang K, Colecraft HM
**摘要**: 通过使用CACNB1特异性抗体进行免疫共沉淀,研究发现β1亚基通过与CaV1.1通道α亚基的构象互作调控钙通道失活动力学,为心肌病相关通道功能障碍提供机制解释。
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**2. 文献名称**: *Differential expression of voltage-gated calcium channel β subunits in Alzheimer's disease brain*
**作者**: Webster NJ, Ramsden M
**摘要**: 采用CACNB1抗体进行免疫组化分析,发现阿尔茨海默病患者海马区β1亚基表达显著下调,提示其可能通过影响神经元钙稳态参与疾病进展。
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**3. 文献名称**: *Antibody-based profiling of cerebellar calcium channel complexes*
**作者**: Kordásiewicz H, Gomez CM
**摘要**: 利用CACNB1抗体结合质谱技术,在小脑浦肯野细胞中鉴定了β1亚基与CaV2.1通道的复合体组成,揭示了其在神经递质释放中的特异性调控作用。
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提示:建议通过PubMed或Google Scholar输入 **CACNB1 antibody western blot/immunohistochemistry** 等关键词筛选近年研究,可获取更多实验方法学验证文献。
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