| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Chaperone activity of bc1 complex-like, mitochondrial, Chaperone-ABC1-like, 2711-, aarF domain-containing protein kinase 3, Adck3, Cabc1 |
| Entrez GeneID | 67426 |
| WB Predicted band size | 71.7kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Mouse |
| Immunogen | This Mouse Cabc1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-423 amino acids from the Central region of mouse Cabc1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于Mouse CABc1抗体的虚构参考文献示例(请注意，CABc1可能为假设名称，实际文献需根据具体基因/蛋白名称检索)：
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1. **文献名称**: "Characterization of CABc1 in Mouse Liver Development"
**作者**: Smith A, et al.
**摘要**: 本研究利用抗小鼠CABc1抗体进行免疫组化分析，揭示其在肝脏发育过程中于胆管上皮细胞的动态表达，提示CABc1可能参与胆汁酸转运调控。
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2. **文献名称**: "CABc1 Antibody Validation for Western Blot Applications"
**作者**: Lee J, et al.
**摘要**: 通过基因敲除小鼠模型验证抗CABc1抗体的特异性，确认其在Western blot中可检测约75 kDa的目标蛋白，为代谢疾病研究提供可靠工具。
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3. **文献名称**: "Role of CABc1 in Neuronal Cholesterol Homeostasis"
**作者**: Garcia R, et al.
**摘要**: 使用小鼠脑组织切片进行免疫荧光染色，发现CABc1蛋白定位于神经元突触膜，其缺失导致胆固醇堆积，暗示其在神经系统脂质代谢中的关键作用。
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**注**：若"CABc1"为假设名称或拼写误差，建议核实目标蛋白标准命名(如ABCA1/ABCC1等)后重新检索文献。实际文献可通过PubMed、Google Scholar等平台以“CABc1 antibody mouse”为关键词查找。
The Mouse Cabc1 antibody is a monoclonal or polyclonal immunoglobulin designed to specifically recognize and bind to the Cabc1 protein in murine samples. Cabc1 (Calcium-binding and coiled-coil domain-containing protein 1), also known as CALCOCO1 or NDDP, is a conserved eukaryotic protein involved in intracellular trafficking, autophagy, and membrane dynamics. It interacts with components of the cytoskeleton and vesicular transport systems, playing roles in Golgi-to-lysosome trafficking and selective autophagy pathways, such as xenophagy (targeting pathogens) and aggrephagy (clearing protein aggregates).
Cabc1 antibodies are widely used in research applications like Western blotting, immunofluorescence, and immunoprecipitation to study Cabc1 expression, localization, and interactions in cellular models. These tools help elucidate Cabc1’s regulatory mechanisms in physiological processes and diseases, including neurodegenerative disorders, cancer, and immune responses. The development of Cabc1 antibodies in mouse hosts often involves immunizing with recombinant Cabc1 protein fragments, followed by hybridoma generation (for monoclonal types) or serum purification (polyclonal). Validation typically includes knockout cell controls to confirm specificity. As Cabc1 gains attention for its dual roles in autophagy and innate immunity, its antibodies remain critical for dissecting molecular pathways in both normal and pathological states.
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