WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Acyl-CoA-binding domain-containing protein 7, ACBD7 |
Entrez GeneID | 414149 |
WB Predicted band size | 9.8kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | This ACBD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-88 amino acids from the C-terminal region of human ACBD7. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是模拟的关于ACBD7抗体的参考文献示例(注:实际文献可能有限,建议通过学术数据库核实):
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1. **文献名称**: *"ACBD7 modulates peroxisome-mitochondria interaction through lipid metabolism in hepatocellular carcinoma"*
**作者**: Zhang Y, et al.
**摘要**: 本研究利用特异性ACBD7抗体,揭示了ACBD7通过结合脂肪酸调节过氧化物酶体与线粒体间的膜接触,促进肝癌细胞能量代谢及生长。
2. **文献名称**: *"Generation and validation of a polyclonal antibody for ACBD7 subcellular localization studies"*
**作者**: Smith JL, et al.
**摘要**: 报道一种新型ACBD7多克隆抗体的开发,通过免疫印迹和免疫荧光验证其特异性,证实ACBD7主要定位于细胞质,可能与内质网功能相关。
3. **文献名称**: *"ACBD7 as a potential biomarker in neurodegenerative diseases: antibody-based detection in cerebrospinal fluid"*
**作者**: Lee S, et al.
**摘要**: 采用ACBD7抗体进行ELISA检测,发现阿尔茨海默病患者脑脊液中ACBD7水平显著升高,提示其可能参与神经退行性病理过程。
4. **文献名称**: *"ACBD7 antibody reveals its role in viral RNA replication via organelle membrane remodeling"*
**作者**: Chen R, et al.
**摘要**: 通过ACBD7抗体阻断实验,发现ACBD7与病毒复制复合体在重塑细胞器膜结构中的作用,为抗病毒治疗提供新靶点。
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**注意**:以上内容为模拟生成,ACBD7相关研究在真实数据库中可能较少。建议使用PubMed、Google Scholar等平台,以“ACBD7 antibody”或“ACBD7 function”为关键词检索最新文献。若研究稀缺,可扩展至ACBD蛋白家族(如ACBD3/ACBD5)或相关通路。
The ACBD7 antibody targets the Acyl-CoA-binding domain-containing protein 7 (ACBD7), a member of the ACBD protein family implicated in lipid metabolism, intracellular trafficking, and organelle interactions. ACBD7. though less characterized compared to other ACBD members (e.g., ACBD3 or ACBD1), is believed to play roles in acyl-CoA binding, lipid transport, or signaling pathways. Its expression has been detected in various tissues, with potential relevance to metabolic or neurological disorders, though specific biological functions remain under investigation.
The ACBD7 antibody is typically developed as a polyclonal or monoclonal tool for research applications, enabling detection of endogenous ACBD7 protein in techniques like Western blotting, immunohistochemistry, or immunofluorescence. Validation often includes knockout controls or siRNA knockdown to confirm specificity. Limited commercial availability suggests its primary use in exploratory studies. Current research focuses on elucidating ACBD7's interaction partners, subcellular localization (e.g., Golgi, endoplasmic reticulum), and potential involvement in diseases like cancer or neurodegenerative conditions. Challenges include the protein's low abundance and overlapping functions with other ACBD proteins, necessitating cautious interpretation of experimental results. Further studies are required to define its precise physiological and pathological roles.
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