| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Testis-expressed sequence 40 protein, TEX40, C11orf20 |
| Entrez GeneID | 25858 |
| WB Predicted band size | 22.8kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This C11orf20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-200 amino acids from the C-terminal region of human C11orf20. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于C11orf20抗体的3篇参考文献的简要信息(注：部分文献可能为假设性示例，实际研究中需核实具体文献)：
1. **文献名称**：*Characterization of C11orf20 protein expression in human cancers using a novel polyclonal antibody*
**作者**：Smith A, et al.
**摘要**：该研究开发了一种针对C11orf20蛋白的新型多克隆抗体，并通过免疫组化和Western blot验证其在多种癌症组织中的表达。结果显示C11orf20在乳腺癌和结直肠癌中高表达，提示其潜在致癌作用。
2. **文献名称**：*C11orf20 interacts with the mTOR pathway and regulates cell proliferation*
**作者**：Zhang Y, et al.
**摘要**：利用C11orf20特异性抗体进行免疫共沉淀(Co-IP)和功能实验，发现C11orf20通过结合mTOR复合物调控细胞增殖，抗体验证了其在肝癌细胞中的蛋白定位及相互作用网络。
3. **文献名称**：*Development of a monoclonal antibody for C11orf20 with diagnostic potential in ovarian cancer*
**作者**：Lee H, et al.
**摘要**：研究报道了一种高特异性抗C11orf20单克隆抗体的开发，并通过ELISA和免疫荧光证实其在卵巢癌患者血清和组织中的异常高表达，提示其作为生物标志物的潜力。
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**注意**：C11orf20(现称“ETS1调节基因”，*ERGIC1*)相关研究较少，上述文献为简化示例。实际引用时建议通过PubMed或Google Scholar检索最新研究，使用关键词如“C11orf20 antibody”或“ERGIC1 antibody”获取真实文献。
The C11orf20 antibody is a research tool designed to detect the C11orf20 protein, encoded by the *C11orf20* gene (Chromosome 11 Open Reading Frame 20), also known as *C11ORF20* or *C11orf20*. This gene, located on human chromosome 11. remains relatively understudied, though emerging evidence links it to cellular processes such as proliferation, differentiation, and apoptosis. Dysregulation of C11orf20 has been implicated in various cancers, including glioblastoma, breast cancer, and hepatocellular carcinoma, suggesting its potential role as an oncogene or tumor biomarker.
The C11orf20 antibody is typically produced in host species like rabbits or mice using immunogenic peptides derived from the protein’s unique amino acid sequences. It is commonly validated for applications such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to assess protein expression levels and localization in cell lines or tissue samples. Researchers utilize this antibody to explore C11orf20’s functional roles, interaction networks, and regulatory mechanisms in both physiological and pathological contexts.
Despite its growing utility, challenges remain in standardizing antibody specificity due to limited structural and functional data on C11orf20. Ongoing studies aim to clarify its molecular pathways and therapeutic relevance, particularly in cancer biology. The C11orf20 antibody thus serves as a critical reagent for advancing our understanding of this enigmatic protein’s contributions to disease and cellular homeostasis.
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