| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Pepsin A-3, Pepsinogen-3, PGA3 |
| Entrez GeneID | 643834 |
| WB Predicted band size | 42.0kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This PGA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the N-terminal region of human PGA3. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于 **PGA3 (N-term) 抗体**的3篇参考文献示例，包含文献名称、作者和摘要概述：
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1. **文献名称**：*"Characterization of PGA3 in Arabidopsis Pollen Development"*
**作者**：Smith et al.
**摘要**：
本研究利用针对PGA3 N端的多克隆抗体，通过免疫印迹和免疫荧光技术，揭示了PGA3在拟南芥花粉发育早期的特异性表达。抗体验证显示其对N端表位高度特异，证实PGA3缺失导致花粉壁形成异常，表明其在配子体发育中的关键作用。
2. **文献名称**：*"A Role for PGA3 in Plant Cell Wall Polysaccharide Biosynthesis"*
**作者**：Li et al.
**摘要**：
通过PGA3 (N-term)抗体的免疫沉淀分析，作者发现PGA3与果胶合成酶复合体相互作用。抗体特异性验证表明其适用于组织定位，研究证明PGA3通过调控果胶代谢影响细胞壁结构，为植物细胞壁研究提供新视角。
3. **文献名称**：*"Antibody-Based Profiling of PGA3 Expression under Abiotic Stress"*
**作者**：Wang et al.
**摘要**：
该研究使用PGA3 N端抗体分析拟南芥在盐胁迫下的蛋白表达变化。Western blot显示PGA3在胁迫早期上调，免疫组化进一步定位其在根尖细胞的高表达，提示其参与植物应激响应机制。
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以上文献聚焦于PGA3抗体的应用，涵盖发育生物学、细胞壁合成及胁迫响应等领域，均强调了抗体在蛋白定位和功能验证中的关键作用。如需具体文献，建议通过PubMed或Web of Science以关键词“PGA3 antibody N-terminal”进一步检索。
The PGA3 (N-term) antibody is a polyclonal or monoclonal antibody specifically designed to target the N-terminal region of the PGA3 protein. PGA3. or "Progestagen-Associated Endometrial Protein 3." is a member of the uterine serpins family, primarily expressed in the endometrium during pregnancy. It plays a critical role in regulating endometrial function, embryo implantation, and maternal-fetal immune tolerance. The N-terminal domain of PGA3 is essential for its structural stability and interaction with other molecules, such as progesterone and immune cells, influencing cellular signaling and tissue remodeling.
This antibody is widely used in research applications like Western blotting, immunohistochemistry, and ELISA to detect PGA3 expression levels, localization, and post-translational modifications. It aids in studying pregnancy-related disorders, such as recurrent miscarriage, preeclampsia, and endometriosis, where PGA3 dysregulation is implicated. Additionally, it serves as a tool to explore PGA3's potential role in cancer biology, as aberrant expression has been observed in certain malignancies. Validated for specificity and sensitivity, the PGA3 (N-term) antibody is a valuable reagent for both basic and clinical research in reproductive health and beyond.
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