| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Zinc finger protein-like 1, Zinc finger protein MCG4, ZFPL1 |
| Entrez GeneID | 7542 |
| WB Predicted band size | 34.1kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This ZFPL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the Central region of human ZFPL1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于ZFPL1抗体的3篇虚构参考文献示例(注：以下内容为模拟创作，实际文献需通过学术数据库查询)：
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1. **文献名称**: "ZFPL1 is essential for maintaining Golgi structure and function in mammalian cells"
**作者**: Zhang et al., 2018
**摘要**: 本研究利用特异性ZFPL1抗体，证实ZFPL1蛋白通过调控高尔基体相关蛋白复合物的稳定性维持其结构完整性。基因敲除实验显示，ZFPL1缺失会导致高尔基体碎片化并影响分泌途径功能。
2. **文献名称**: "ZFPL1 deficiency disrupts acrosome formation during spermatogenesis"
**作者**: Lee et al., 2020
**摘要**: 通过免疫荧光和Western blot分析(使用兔源多克隆ZFPL1抗体)，发现ZFPL1在小鼠精子顶体形成中起关键作用。敲除模型显示精子形态异常及雄性不育表型。
3. **文献名称**: "ZFPL1 interacts with herpes simplex virus 1 glycoproteins to promote viral assembly"
**作者**: Chen et al., 2021
**摘要**: 研究通过免疫共沉淀(抗ZFPL1抗体)和电镜技术，揭示ZFPL1与HSV-1病毒糖蛋白相互作用，促进病毒粒子在高尔基体区域的组装，为抗病毒靶点提供新思路。
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如需真实文献，建议通过PubMed或Google Scholar以“ZFPL1 antibody”或“ZFPL1 function”为关键词检索，并筛选涉及该抗体应用的实验研究(如Western blot、免疫组化等)。
ZFPL1 (Zinc Finger Protein-Like 1) is a conserved transmembrane protein localized to the Golgi apparatus, implicated in maintaining Golgi structure and vesicular trafficking. It contains a zinc finger domain, suggesting potential roles in protein-protein or protein-membrane interactions. ZFPL1 is ubiquitously expressed across tissues, with studies linking it to the regulation of Golgi ribbon formation and secretion pathways. Its dysfunction has been tentatively associated with neurological disorders and cancer, though mechanistic insights remain limited.
ZFPL1 antibodies are immunological tools developed to detect and study this protein's expression, localization, and function. Commonly generated in hosts like rabbits or mice, these antibodies are validated for applications such as Western blotting, immunofluorescence, and immunoprecipitation. Specificity is often confirmed using ZFPL1 knockout cell lines or tissues. Commercial antibodies typically target epitopes within the N-terminal cytoplasmic domain or C-terminal regions.
Research using ZFPL1 antibodies has helped clarify its interaction with Golgi matrix proteins like GRASP55 and its role in cargo transport. However, antibody performance may vary between experimental models due to post-translational modifications or species-specific sequence differences. Recent studies employ these antibodies to explore ZFPL1's potential involvement in cellular stress responses and neurodegenerative disease pathways, emphasizing its emerging significance in cell biology and pathophysiology.
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