WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MAPK/ERK kinase 5, MEK 5, Map2k5, Mek5, Mkk5, Prkmk5 |
Entrez GeneID | 23938 |
WB Predicted band size | 50.1kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | This Mouse Map2k5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-412 amino acids from the C-terminal region of mouse Map2k5. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是几篇关于Mouse Map2k5(MEK5)抗体的示例参考文献(注:以下为虚构示例,实际文献需通过学术数据库检索验证):
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1. **"Characterization of a novel monoclonal antibody targeting Map2k5 in murine models"**
*Authors: Tanaka H, et al.*
摘要:本研究开发了一种针对小鼠Map2k5蛋白的单克隆抗体,验证了其在Western blot和免疫组织化学中的特异性。实验证明该抗体可特异性识别小鼠心脏和脑组织中的Map2k5.并在Map2k5基因敲除模型中显示无交叉反应性。
2. **"Map2k5 signaling in cardiac hypertrophy: Insights from antibody-based inhibition studies"**
*Authors: Smith JL, et al.*
摘要:通过使用小鼠Map2k5特异性抗体,研究发现Map2k5在压力超负荷诱导的心肌肥厚中显著激活。抗体阻断实验表明,抑制Map2k5可减轻心肌细胞肥大表型,提示其作为治疗靶点的潜力。
3. **"Dysregulation of MEK5/ERK5 pathway in neurodegenerative disorders: Evidence from mouse models"**
*Authors: Chen R, et al.*
摘要:利用Map2k5抗体分析阿尔茨海默病模型小鼠脑组织,发现MEK5/ERK5通路活性降低与tau蛋白异常磷酸化相关。抗体染色显示Map2k5在神经元中的定位与疾病进展相关。
4. **"Validation of commercial Map2k5 antibodies for murine tissue-specific applications"**
*Authors: Gonzalez P, et al.*
摘要:系统性评估了多种市售小鼠Map2k5抗体的灵敏度与特异性,推荐适用于不同实验场景(如流式细胞术、免疫沉淀)的抗体,并提供了组织裂解液制备的优化方案。
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**建议**:实际文献可通过PubMed或Google Scholar以关键词“MEK5 antibody mouse”“Map2k5 signaling”或“MEK5/ERK5 pathway”检索,并优先选择近5年内的研究以获取最新进展。
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