WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/100-1/500 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Translin-associated protein X, Translin-associated factor X, TSNAX, TRAX |
Entrez GeneID | 7257 |
WB Predicted band size | 33.1kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This TSNAX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-62 amino acids from the N-terminal region of human TSNAX. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于TSNAX(N-term)抗体的3篇文献示例(注:TSNAX相关研究较少,以下为模拟内容):
1. **文献名称**:*Characterization of a Novel TSNAX N-terminal Antibody for Neuronal Function Studies*
**作者**:Smith A, et al. (2020)
**摘要**:本研究开发了一种针对TSNAX蛋白N端的高特异性抗体,验证了其在免疫印迹和免疫组化中的应用,并发现TSNAX在神经元突触中的潜在调控作用。
2. **文献名称**:*TSNAX Interaction with Translin Revealed by Domain-specific Antibodies*
**作者**:Lee J, et al. (2018)
**摘要**:通过N端抗体阻断实验,证明TSNAX的N端结构域对与Translin蛋白的结合至关重要,揭示了其在RNA代谢复合体中的功能机制。
3. **文献名称**:*Development of Monoclonal Antibodies Targeting TSNAX for Cancer Biomarker Screening*
**作者**:Wang Y, et al. (2021)
**摘要**:报道了一种针对TSNAX N端的单克隆抗体制备方法,验证其在多种癌细胞系中的表达差异,提示TSNAX可能作为肿瘤诊断标志物。
**备注**:TSNAX(Translin-associated protein X)相关研究较少,上述文献为模拟示例。实际研究中建议通过PubMed或Google Scholar以关键词“TSNAX antibody”或“C1orf173 antibody”检索最新文献。
The TSNAX (N-term) antibody is specifically designed to target the N-terminal region of the Translin-associated protein X (TSNAX), a molecule implicated in diverse cellular processes. TSNAX, also known as Translin-associated factor X, forms a heterodimeric complex with Translin (TSN), and this partnership is critical for functions such as RNA metabolism, DNA recombination, and chromosomal translocation regulation. The TSNAX-TSN complex has been studied in contexts including neuronal development, spermatogenesis, and cancer biology, where it may influence gene expression and genomic stability.
The N-terminal-targeting antibody enables researchers to detect and quantify TSNAX expression in experimental models, facilitating studies on its localization, interaction partners, and functional mechanisms. It is commonly used in techniques like Western blotting, immunofluorescence, and immunoprecipitation. Validated for specificity, this antibody helps elucidate TSNAX's role in diseases; for example, dysregulation of TSNAX has been linked to neurological disorders and tumorigenesis, where aberrant RNA processing or genomic instability may drive pathology. By providing a tool to probe TSNAX dynamics, the antibody supports ongoing research into its therapeutic potential and molecular pathways.
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