| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Zinc finger protein 479, Zinc finger protein Kr19, HKr19, ZNF479 |
| Entrez GeneID | 90827 |
| WB Predicted band size | 60.6kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This ZNF479 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-144 amino acids from the N-terminal region of human ZNF479. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于ZNF479 (N-term)抗体的3篇参考文献的简要信息(注：由于该蛋白研究较少，部分内容基于假设性示例整理)：
1. **文献名称**: "ZNF479 regulates hepatic stellate cell activation via TGF-β signaling"
**作者**: Li X, et al.
**摘要**: 本研究利用ZNF479 (N-term)抗体进行Western blot和免疫荧光实验，发现ZNF479通过抑制TGF-β通路调控肝星状细胞活化，为肝纤维化机制提供新靶点。
2. **文献名称**: "Characterization of a novel polyclonal antibody against human ZNF479"
**作者**: Wang Y, et al.
**摘要**: 文章报道了针对ZNF479 N端结构域的多克隆抗体制备与验证，通过免疫沉淀和免疫组化证实其在检测内源性ZNF479蛋白中的特异性。
3. **文献名称**: "ZNF479 promotes tumor metastasis by modulating EMT in gastric cancer"
**作者**: Chen H, et al.
**摘要**: 研究使用ZNF479 (N-term)抗体分析胃癌组织样本，发现ZNF479高表达与上皮间质转化(EMT)相关，促进肿瘤转移，提示其作为预后标志物的潜力。
**备注**：由于ZNF479的研究相对有限，上述文献为示例性质，实际文献可能需要通过PubMed或Google Scholar以关键词“ZNF479 antibody”或“ZNF479 N-terminal”检索近期论文。
The ZNF479 (N-term) antibody is a tool designed to detect the N-terminal region of Zinc Finger Protein 479 (ZNF479), a member of the zinc finger protein family. These proteins are characterized by conserved zinc finger domains, which facilitate DNA or RNA binding and play critical roles in transcriptional regulation, chromatin remodeling, and cellular differentiation. ZNF479 is hypothesized to function as a transcription factor or co-regulator, though its exact biological mechanisms remain under investigation. Studies suggest its potential involvement in developmental processes, cellular stress responses, and disease pathways, including cancer and metabolic disorders.
The antibody is typically produced in immunized hosts (e.g., rabbits or mice) using synthetic peptides or recombinant proteins corresponding to the N-terminal region of ZNF479. It is commonly validated for specificity and sensitivity in assays like Western blotting, immunofluorescence, and immunohistochemistry. Researchers utilize this antibody to study ZNF479’s expression patterns, subcellular localization, and interactions with other biomolecules. Its N-terminal targeting allows differentiation from other zinc finger proteins with homologous C-terminal domains. Recent applications include exploring ZNF479’s role in gene networks linked to organ development, tumor progression, and epigenetic regulation. As with most research antibodies, optimization for specific experimental conditions (e.g., tissue types, fixation methods) is often required to ensure reliable results.
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