| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | AI451071; cAMP dependent protein kinase type II beta regulatory chain; Pkarb2; PRKAR2B; Protein kinase cAMP dependent regulatory type II beta; RATDNA; RII beta;;PRKAR2B |
| WB Predicted band size | 46 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human PRKAR2B |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
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以下是关于ITGAL(CD11a)抗体的模拟参考文献示例，供参考：
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1. **文献名称**：*Targeting LFA-1 with a Novel Antibody Inhibits T Cell-Mediated Inflammation*
**作者**：Smith A, et al.
**摘要**：研究报道了一种靶向ITGAL(CD11a)的新型单克隆抗体，通过阻断LFA-1与ICAM-1的相互作用，显著抑制T细胞介导的炎症反应。实验显示该抗体在自身免疫性疾病小鼠模型中减轻了组织损伤。
2. **文献名称**：*Structural Basis of CD11a Monoclonal Antibody Therapeutic Efficacy in Psoriasis*
**作者**：Lee B, et al.
**摘要**：通过冷冻电镜技术解析了人源化抗ITGAL抗体(Efalizumab)与CD11a的结合表位，揭示了其抑制LFA-1活化构象的分子机制，为银屑病治疗的优化提供了结构学依据。
3. **文献名称**：*CD11a Antibody Prolongs Allograft Survival by Modulating Dendritic Cell Function*
**作者**：Chen X, et al.
**摘要**：研究表明，抗ITGAL抗体通过抑制树突状细胞表面CD11a的活性，降低同种异体移植中的T细胞活化，显著延长小鼠心脏移植模型的移植物存活时间。
4. **文献名称**：*ITGAL Gene Variants and Antibody Response in Autoimmunity*
**作者**：Garcia-Ramos R, et al.
**摘要**：分析了ITGAL基因多态性与抗CD11a自身抗体的关联性，发现特定单核苷酸多态性(SNP)可能影响系统性红斑狼疮(SLE)患者中抗体的产生及疾病严重程度。
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注：以上文献为示例性内容，实际引用时请通过PubMed或学术数据库核实真实文献。如需具体论文，可检索关键词如“ITGAL antibody”、“LFA-1 blockade”或“CD11a therapeutic”。
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