关键信息
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基因名
JMJD8
- 应用
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别名
(Jumonji domain-containing protein 8)
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种属
Human
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96S16
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表达区间
24-264aa
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分子量
34.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
JMJD8 (Jumonji domain-containing protein 8) is a member of the Jumonji C (JmjC) domain-containing family of proteins, which are known for their role as histone demethylases, regulating gene expression through epigenetic modifications. The research on JMJD8 has garnered interest due to its involvement in various biological processes, including cellular differentiation, development, and response to stress. Recent studies have suggested that JMJD8 is implicated in the regulation of key signaling pathways and may play a role in specific diseases, including cancer and metabolic disorders. The ability of JMJD8 to modify histones and other substrates positions it as a potential therapeutic target, making the understanding of its structure and function crucial. Recombinant JMJD8 protein production allows researchers to investigate its biochemical properties, binding interactions, and functional mechanisms in detail. By utilizing advanced techniques such as crystallography and mass spectrometry, scientists aim to uncover the precise role of JMJD8 in cellular processes and its potential implications in disease. This research not only adds to the fundamental knowledge of epigenetic regulators but also explores the therapeutic possibilities of targeting JMJD8 in disease management.
