| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Tubulin alpha-3C/D chain, Alpha-tubulin 2, Alpha-tubulin 3C/D, Tubulin alpha-2 chain, TUBA3C, TUBA2 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This TUBA3C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 413-441 amino acids from the C-terminal region of human TUBA3C. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于TUBA3C抗体的3篇模拟参考文献(注：TUBA3C研究较少，以下为示例性虚构内容，建议通过PubMed或Google Scholar查询真实文献)：
1. **标题**: "TUBA3C as a novel biomarker in lung adenocarcinoma: Validation of a specific polyclonal antibody"
**作者**: Zhang L, et al.
**摘要**: 本研究开发了一种针对TUBA3C的新型兔源多克隆抗体，通过Western blot和免疫组化验证其在肺癌组织中的特异性表达，发现TUBA3C高表达与患者预后不良相关。
2. **标题**: "Characterization of TUBA3C monoclonal antibody for neuronal differentiation studies"
**作者**: Müller S, et al.
**摘要**: 报道了一种高特异性的TUBA3C单克隆抗体的开发，通过免疫荧光和流式细胞术证实其在神经干细胞分化过程中微管动态变化的检测能力。
3. **标题**: "TUBA3C antibody cross-reactivity analysis reveals isoform-specific functions in colorectal cancer"
**作者**: Tanaka K, et al.
**摘要**: 利用CRISPR敲除模型验证TUBA3C抗体的特异性，发现该抗体可区分TUBA3C与其他α-微管蛋白亚型，并揭示其在结直肠癌转移中的独特调控作用。
**提示**：实际研究中，TUBA3C相关文献较少，建议关注以下方向：
- 使用抗体数据库(如CiteAb)查询商品化抗体对应的引用文献
- 结合"α-tubulin isoform"或"tubulin family antibody"等关键词扩展检索
- 查阅涉及微管蛋白亚型功能研究的综述文献
The TUBA3C antibody targets Tubulin Alpha 3c (TUBA3C), a member of the α-tubulin protein family, which is critical for microtubule formation and cellular processes like mitosis, intracellular transport, and cytoskeletal organization. TUBA3C, encoded by the TUBA3C gene, is one of multiple α-tubulin isotypes with tissue-specific expression patterns. While its exact functional distinctions from other α-tubulins remain under study, TUBA3C is implicated in developmental and disease contexts, including cancer, where altered tubulin expression may influence drug resistance or metastasis.
TUBA3C antibodies are widely used as research tools to detect protein expression, localization, and dynamics in cells or tissues. They enable applications such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Due to high sequence homology among α-tubulin isoforms, TUBA3C-specific antibodies require rigorous validation to ensure selectivity, often achieved through knockout controls or epitope mapping. Commercial TUBA3C antibodies are typically raised against recombinant proteins or synthetic peptides corresponding to unique regions of the TUBA3C sequence.
Research involving TUBA3C antibodies spans neurobiology, cancer biology, and developmental studies, particularly in exploring microtubule-related pathologies or TUBA3C's role as a potential biomarker. However, variability in antibody performance across experimental conditions underscores the need for careful optimization in each application.
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