WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/100-1/500 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Transducin-like enhancer protein 6, TLE6 |
Entrez GeneID | 79816 |
WB Predicted band size | 63.5kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This TLE6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the N-terminal region of human TLE6. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于 TLE6 (N-term) 抗体的 3 篇参考文献示例(注:文献为虚构示例,实际需根据具体数据库检索补充):
1. **文献名称**:*"TLE6 as a novel biomarker in ovarian cancer: Expression analysis using N-terminal specific antibodies"*
**作者**:Smith A, et al.
**摘要**:本研究利用针对 TLE6 N 端的特异性抗体,通过免疫组化(IHC)和蛋白质印迹(Western blot)技术,揭示了 TLE6 在卵巢癌组织中的高表达现象,并发现其与患者不良预后显著相关。
2. **文献名称**:*"Functional characterization of TLE6 in embryonic stem cell pluripotency via CRISPR/Cas9 and antibody-mediated protein localization"*
**作者**:Zhang L, et al.
**摘要**:通过 CRISPR/Cas9 敲除技术和 TLE6 N 端抗体的免疫荧光染色,研究者证实 TLE6 在维持小鼠胚胎干细胞多能性中起关键作用,并参与调控 Wnt 信号通路。
3. **文献名称**:*"Interactions between TLE6 and SMAD3 in TGF-β signaling pathway revealed by co-immunoprecipitation assays"*
**作者**:Johnson R, et al.
**摘要**:使用 TLE6 N 端抗体进行免疫共沉淀(Co-IP)实验,发现 TLE6 与 SMAD3 蛋白存在直接相互作用,为 TGF-β 信号通路的调控机制提供了新证据。
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**备注**:实际文献需通过 PubMed、Google Scholar 或抗体供应商(如 CST、Abcam)官网的引用列表检索,建议结合关键词 **"TLE6 antibody N-terminal"** 或 **"TLE6 immunolocalization"** 进一步筛选。
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