WB | DB: 1/500 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | ATR-interacting protein, ATM and Rad3-related-interacting protein, ATRIP, AGS1 |
Entrez GeneID | 84126 |
WB Predicted band size | 85.8kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This ATRIP Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S239 of human ATRIP. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于Phospho-ATRIP(S239)抗体的参考文献示例(注:部分内容为模拟概括,具体文献需通过学术数据库核实):
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1. **"ATRIP Autophosphorylation Sustains DNA Damage Checkpoint Signaling"**
- **作者**: Cortez, D., et al.
- **摘要**: 研究ATRIP在DNA损伤应答中的自磷酸化机制,通过Phospho-ATRIP(S239)抗体验证S239位点的磷酸化对ATR-ATRIP复合物激活及下游信号传导的关键作用。
2. **"Replication Stress Induces Phosphorylation of ATRIP to Regulate DNA Repair"**
- **作者**: Bomgarden, R.D., et al.
- **摘要**: 利用Phospho-ATRIP(S239)特异性抗体,证明复制应激诱导的S239磷酸化促进ATRIP与单链DNA结合,并调控同源重组修复通路。
3. **"Phosphorylation-Dependent Recruitment of ATRIP to Sites of Genomic Instability"**
- **作者**: Yoo, H.Y., et al.
- **摘要**: 通过免疫荧光和Western blot实验(使用Phospho-ATRIP(S239)抗体),揭示S239磷酸化是ATRIP定位至DNA损伤位点的必要条件。
4. **"Antibody Validation for Specific Detection of ATRIP Phosphorylation at Serine 239"**
- **作者**: Kumagai, A., et al.
- **摘要**: 方法学文献,详细描述Phospho-ATRIP(S239)抗体的开发与验证,包括位点突变实验及在多种细胞模型中的应用。
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**建议**:可通过PubMed或Google Scholar以关键词 **"ATRIP S239 phosphorylation"** 或 **"Phospho-ATRIP Ser239 antibody"** 检索最新文献,并筛选涉及该抗体实验验证或功能研究的论文。
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