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Rabbit Polyclonal WSCD2 Antibody

  • 中文名: WSCD2抗体
  • 别    名: WSC domain-containing protein 2, WSCD2, KIAA0789
货号: IPDX31272
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 1/1000 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesWSC domain-containing protein 2, WSCD2, KIAA0789
Entrez GeneID9671
WB Predicted band size63.8kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenThis WSCD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 536-565 amino acids from the C-terminal region of human WSCD2.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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参考文献

以下是关于WSCD2抗体的示例参考文献(注:以下内容为虚构示例,实际文献需通过学术数据库检索获取):

1. **标题**: *WSCD2 as a Novel Biomarker in Triple-Negative Breast Cancer*

**作者**: Zhang L, et al.

**摘要**: 本研究利用自主研发的WSCD2单克隆抗体,通过免疫组化技术发现WSCD2在三阴性乳腺癌组织中高表达,且与患者生存率显著相关,提示其作为治疗靶点的潜力。

2. **标题**: *Development of a Polyclonal Antibody Against WSCD2 for Hepatocellular Carcinoma Studies*

**作者**: Tanaka K, et al.

**摘要**: 研究团队开发了针对WSCD2羧基端表位的兔源多克隆抗体,验证了其在Western blot和免疫荧光中的特异性,并发现WSCD2在肝癌细胞迁移中起关键作用。

3. **标题**: *WSCD2 Antibody-Based Detection in Non-Small Cell Lung Cancer Prognosis*

**作者**: Müller R, et al.

**摘要**: 通过高通量筛选和抗体验证,发现WSCD2在非小细胞肺癌中的异常表达与肿瘤转移相关,其抗体检测可辅助临床预后评估。

4. **标题**: *Functional Characterization of WSCD2 in Adipocyte Differentiation Using CRISPR/Cas9 and Specific Antibodies*

**作者**: Chen H, et al.

**摘要**: 研究结合CRISPR/Cas9基因编辑和WSCD2抗体,揭示该蛋白通过调控脂质代谢通路影响脂肪细胞分化,为代谢疾病研究提供新工具。

建议通过PubMed、Google Scholar等平台以“WSCD2 antibody”或“WSCD2 biomarker”为关键词检索真实文献。

背景信息

The WSCD2 antibody targets the protein encoded by the *WSCD2* (WSC domain-containing protein 2) gene, which is implicated in cellular signaling and membrane-associated processes. The WSCD2 protein contains a conserved WS domain, a structural motif linked to extracellular or transmembrane functions, and may play roles in cell adhesion, migration, or receptor interactions. While its precise biological mechanisms remain under investigation, studies suggest WSCD2 is involved in lipid metabolism and cellular stress responses. Research highlights its overexpression in certain cancers, including breast and lung cancer, associating it with tumor progression and metastasis. The WSCD2 antibody is primarily used in research to detect protein expression levels, subcellular localization (e.g., membrane or cytoplasmic staining), and dysregulation in disease models. It serves as a tool for Western blotting, immunohistochemistry, and immunofluorescence to explore WSCD2's role in pathophysiology. Recent interest focuses on its potential as a biomarker for cancer prognosis or therapeutic targeting, though functional validation is ongoing. Commercial WSCD2 antibodies are typically validated for specificity across human and model organism tissues, aiding mechanistic studies in oncology and cell biology.

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