关键信息
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基因名
pmpD
- 应用
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别名
Polymorphic membrane protein D
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种属
Chlamydia trachomatis
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O84818
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表达区间
1244-1531aa
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分子量
47.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
PmpD is a significant protein involved in the pathogenicity of various bacterial species, notably in Chlamydia species, which are infamous for causing human infections. Research into PmpD has gained momentum due to its potential role as a virulence factor and its involvement in the immune evasion strategies employed by these pathogens. The protein is thought to facilitate the bacteria's interaction with host cells, promoting infection and chronic disease states. Understanding the structure and function of PmpD provides insight into its mechanisms of action and its potential as a target for therapeutic intervention. The ongoing studies aim to elucidate the molecular pathways that PmpD influences, as well as its interactions with the host immune system, thereby revealing possible strategies for vaccine development or novel antimicrobial therapies. Additionally, characterizing the recombinant PmpD protein continues to be essential for advancing our knowledge of bacterial pathogenesis and improving diagnostic tools. As the research progresses, it holds promise for contributing to more effective approaches in managing infections caused by Chlamydia and related pathogens.
