| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/500 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/10-1/50 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | 40S ribosomal protein S4, Y isoform 1, RPS4Y1, RPS4Y |
| Entrez GeneID | 6192 |
| WB Predicted band size | 29.5kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This RPS4Y1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the Central region of human RPS4Y1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于RPS4Y1抗体的模拟参考文献示例(文献信息为假设，仅供示例参考)：
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1. **文献名称**: *RPS4Y1 Expression in Male Germ Cell Development*
**作者**: Smith A, et al.
**摘要**: 研究报道了RPS4Y1蛋白在人类睾丸组织中的特异性表达，利用定制抗体验证其与精子发生过程的相关性，提示其在男性生殖细胞分化中的潜在功能。
2. **文献名称**: *Antibody Cross-Reactivity of RPS4Y1 in Autoimmune Disorders*
**作者**: Chen L, et al.
**摘要**: 通过免疫印迹和ELISA实验，发现部分系统性红斑狼疮(SLE)女性患者血清中存在抗RPS4Y1抗体，可能与Y染色体蛋白的异常免疫应答相关。
3. **文献名称**: *RPS4Y1 as a Biomarker in Prostate Cancer*
**作者**: Wang X, et al.
**摘要**: 采用抗RPS4Y1抗体对前列腺癌组织进行免疫组化分析，发现其表达水平与肿瘤侵袭性呈正相关，提示其作为男性特异性癌症标志物的潜力。
4. **文献名称**: *Optimization of RPS4Y1 Antibody for Sex-Specific Cell Sorting*
**作者**: Kim H, et al.
**摘要**: 研究开发了一种高特异性抗RPS4Y1单克隆抗体，成功用于流式细胞术分离男性来源的细胞，为性别差异研究提供了可靠工具。
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**备注**：以上文献为假设性示例，实际研究中建议通过学术数据库(如PubMed、Web of Science)检索具体文献。若需真实文献，可提供进一步关键词或研究方向。
The RPS4Y1 antibody targets the ribosomal protein S4. Y-linked 1 (RPS4Y1), a component of the 40S ribosomal subunit encoded by the Y chromosome. As a paralog of RPS4X (X-linked), RPS4Y1 is predominantly expressed in male cells due to its Y-chromosome localization. It plays a role in mRNA binding and ribosome assembly during protein synthesis. The antibody is widely used to study sex-specific differences in cellular processes, particularly in tissues with mosaic gene expression, such as in chimerism or male-derived cell lines.
In research, RPS4Y1 serves as a biomarker for identifying Y-chromosome material in sex determination studies, intersex conditions, or forensic analyses. It also aids in exploring sex-biased diseases, including certain cancers and immune disorders. Commercially available RPS4Y1 antibodies are validated for techniques like Western blotting, immunohistochemistry, and immunofluorescence. Notably, RPS4Y1 expression may vary in Y chromosome aneuploidies (e.g., Turner or Klinefelter syndromes) or during Y chromosome loss in aging males, making the antibody valuable for clinical and aging-related studies. Cross-reactivity with RPS4X requires careful experimental design to ensure specificity in mixed-sex samples.
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